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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1938 1
1953 1
1954 2
1955 1
1957 1
1959 1
1960 2
1961 1
1962 1
1963 3
1964 2
1965 8
1966 4
1967 4
1968 5
1969 6
1970 3
1971 4
1972 2
1973 2
1974 5
1975 8
1976 3
1977 14
1978 16
1979 11
1980 12
1981 10
1982 11
1983 22
1984 24
1985 26
1986 13
1987 10
1988 16
1989 15
1990 11
1991 19
1992 11
1993 10
1994 18
1995 4
1996 11
1997 15
1998 18
1999 18
2000 23
2001 12
2002 15
2003 14
2004 22
2005 18
2006 18
2007 23
2008 30
2009 22
2010 29
2011 29
2012 44
2013 35
2014 23
2015 45
2016 51
2017 36
2018 37
2019 29
2020 34
2021 32
2022 40
2023 46
2024 14

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1,027 results

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Page 1
RIFM fragrance ingredient safety assessment, skatole, CAS Registry Number 83-34-1.
Api AM, Belsito D, Botelho D, Bruze M, Burton GA Jr, Cancellieri MA, Chon H, Dagli ML, Date M, Dekant W, Deodhar C, Fryer AD, Jones L, Joshi K, Kumar M, Lapczynski A, Lavelle M, Lee I, Liebler DC, Moustakas H, Na M, Penning TM, Ritacco G, Romine J, Sadekar N, Schultz TW, Selechnik D, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y. Api AM, et al. Food Chem Toxicol. 2022 Dec;169 Suppl 1:113497. doi: 10.1016/j.fct.2022.113497. Epub 2022 Oct 29. Food Chem Toxicol. 2022. PMID: 36367490 No abstract available.
Skatole: A thin red line between its benefits and toxicity.
Zgarbová E, Vrzal R. Zgarbová E, et al. Biochimie. 2023 May;208:1-12. doi: 10.1016/j.biochi.2022.12.014. Epub 2022 Dec 28. Biochimie. 2023. PMID: 36586563 Review.
Initially, we provide basic knowledge and a historical overview of skatole. Then, skatole bacterial formation in the intestine is described, and the importance of the microbiome during this process is evaluated. ...Ultimately, we suggest a link between skatole …
Initially, we provide basic knowledge and a historical overview of skatole. Then, skatole bacterial formation in the intestine …
Porcine cytochrome 2A19 and 2E1.
Burkina V, Rasmussen MK, Oliinychenko Y, Zamaratskaia G. Burkina V, et al. Basic Clin Pharmacol Toxicol. 2019 Jan;124(1):32-39. doi: 10.1111/bcpt.13121. Epub 2018 Oct 4. Basic Clin Pharmacol Toxicol. 2019. PMID: 30171805 Free PMC article. Review.
Moreover, porcine CYP2A19 and CYP2E1 are responsible for the biotransformation of both endogenous and exogenous compounds such as 3-methylindole (skatole), sex hormones and food compounds. However, little is known about the regulation of porcine CYP2A19 and CYP2E1. ...
Moreover, porcine CYP2A19 and CYP2E1 are responsible for the biotransformation of both endogenous and exogenous compounds such as 3-methylin …
Natural Product Skatole Ameliorates Lipotoxicity-Induced Multiple Hepatic Damage under Hyperlipidemic Conditions in Hepatocytes.
Hong SH, Hong Y, Lee M, Keum BR, Kim GH. Hong SH, et al. Nutrients. 2023 Mar 20;15(6):1490. doi: 10.3390/nu15061490. Nutrients. 2023. PMID: 36986221 Free PMC article.
Skatole has an anti-lipid peroxidation effect and is a biomarker for several diseases. ...Importantly, skatole reduced lipoapoptosis by regulating caspase activity. In conclusion, skatole ameliorated multiple types of hepatocyte damage induced by lipotoxicity …
Skatole has an anti-lipid peroxidation effect and is a biomarker for several diseases. ...Importantly, skatole reduced lipoapo …
The Mode of Action of Chicory Roots on Skatole Production in Entire Male Pigs Is neither via Reducing the Population of Skatole-Producing Bacteria nor via Increased Butyrate Production in the Hindgut.
Li X, Jensen BB, Canibe N. Li X, et al. Appl Environ Microbiol. 2019 Mar 6;85(6):e02327-18. doi: 10.1128/AEM.02327-18. Print 2019 Mar 15. Appl Environ Microbiol. 2019. PMID: 30635386 Free PMC article.
In order to search for other alternatives, more efficient or less expensive, to reduce skatole via feeding, it is important to elucidate the mechanism behind the observed effect of highly fermentable dietary fiber on skatole. Our results indicate that highly ferment …
In order to search for other alternatives, more efficient or less expensive, to reduce skatole via feeding, it is important to elucid …
Novel ECL Method for the Determination of Skatole in Porcine Adipose Tissue.
Stewart S, Scorsone E, Prunier A, Hamel M. Stewart S, et al. Anal Chem. 2022 Apr 26;94(16):6403-6409. doi: 10.1021/acs.analchem.2c00930. Epub 2022 Apr 15. Anal Chem. 2022. PMID: 35427116
A new method for the determination of skatole present in porcine adipose tissue samples utilizing the electrochemiluminescence of skatole is presented. ...Using this principle, a calibration curve using known concentrations of skatole showed good linearity (r …
A new method for the determination of skatole present in porcine adipose tissue samples utilizing the electrochemiluminescence of …
Skatole metabolism in the pigs with reduced testicular oestrogen synthesis.
Zamaratskaia G, Berger T. Zamaratskaia G, et al. Reprod Domest Anim. 2014 Apr;49(2):302-5. doi: 10.1111/rda.12273. Epub 2014 Jan 25. Reprod Domest Anim. 2014. PMID: 24460981
The objectives of the study were to investigate the involvement of oestrogens in the regulation of skatole levels in pigs. In total, 44 intact male pigs, siblings from 10 litters, were included in the study. ...Letrozole treatment did not significantly change either the le …
The objectives of the study were to investigate the involvement of oestrogens in the regulation of skatole levels in pigs. In total, …
Effect of whole foods on the microbial production of tryptophan-derived aryl hydrocarbon receptor agonists in growing pigs.
Huang Z, de Vries S, Fogliano V, Wells JM, van der Wielen N, Capuano E. Huang Z, et al. Food Chem. 2023 Aug 1;416:135804. doi: 10.1016/j.foodchem.2023.135804. Epub 2023 Mar 1. Food Chem. 2023. PMID: 36893645 Free article.
Indole, indole-3-propionic acid, indole-3-acetic acid, indole-3-lactic acid, kynurenine, tryptamine, and indole-3-aldehyde were identified in ileal digesta, which were also identified in faeces but at higher concentrations except indole-3-lactic acid, together with skatole …
Indole, indole-3-propionic acid, indole-3-acetic acid, indole-3-lactic acid, kynurenine, tryptamine, and indole-3-aldehyde were identified i …
Mechanisms of 3-methylindole pneumotoxicity.
Yost GS. Yost GS. Chem Res Toxicol. 1989 Sep-Oct;2(5):273-9. doi: 10.1021/tx00011a001. Chem Res Toxicol. 1989. PMID: 2519817 Review. No abstract available.
1,027 results