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Effects of pumaprazole (BY841), a novel reversible proton pump antagonist, and of omeprazole, on intragastric acidity before and after cure of Helicobacter pylori infection.
Aliment Pharmacol Ther. 1999 Jan;13(1):27-34. doi: 10.1046/j.1365-2036.1999.00440.x.
Aliment Pharmacol Ther. 1999.
PMID: 9892876
Free article.
Clinical Trial.
The 24-h pH values were higher before cure of the infection than after during both pumaprazole (6.0, 4.8-6.7 vs. 4.3, 2.6-5.7; P = 0.002) and omeprazole (5.8, 4.0-6.2 vs. 3.6, 2.8-5; P = 0.004). ...CONCLUSIONS: Both before and after cure of H. pylori infection, pumapraz …
The 24-h pH values were higher before cure of the infection than after during both pumaprazole (6.0, 4.8-6.7 vs. 4.3, 2.6-5.7; P = 0. …
Animal pharmacology of reversible antagonism of the gastric acid pump, compared to standard antisecretory principles.
Kromer W, Postius S, Riedel R.
Kromer W, et al.
Pharmacology. 2000 May;60(4):179-87. doi: 10.1159/000028367.
Pharmacology. 2000.
PMID: 10828742
Regarding the less stringent parameter of inhibition of total acid output in the Heidenhain pouch dog, the modified Shay rat or the Ghosh-Schild rat, pumaprazole is, overall, slightly more efficacious than ranitidine. The M(1)-muscarinic antagonist pirenzepine is ineffecti …
Regarding the less stringent parameter of inhibition of total acid output in the Heidenhain pouch dog, the modified Shay rat or the Ghosh-Sc …
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