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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1934 2
1935 2
1936 2
1937 2
1938 1
1942 1
1945 6
1946 30
1947 25
1948 39
1949 31
1950 111
1951 152
1952 162
1953 151
1954 149
1955 149
1956 140
1957 195
1958 192
1959 195
1960 236
1961 252
1962 334
1963 519
1964 693
1965 539
1966 549
1967 743
1968 874
1969 1039
1970 1117
1971 1094
1972 1195
1973 1357
1974 1526
1975 1543
1976 1359
1977 1369
1978 1287
1979 1475
1980 1480
1981 1444
1982 1453
1983 1445
1984 1518
1985 1495
1986 1463
1987 1449
1988 1442
1989 1529
1990 1591
1991 1503
1992 1541
1993 1519
1994 1451
1995 1540
1996 1415
1997 1444
1998 1405
1999 1417
2000 1536
2001 1515
2002 1506
2003 1530
2004 1478
2005 1611
2006 1650
2007 1581
2008 1614
2009 1570
2010 1523
2011 1538
2012 1615
2013 1597
2014 1556
2015 1572
2016 1509
2017 1446
2018 1503
2019 1447
2020 1446
2021 1390
2022 1474
2023 1363
2024 465

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82,769 results

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Page 1
Classification and pharmacology of progestins.
Schindler AE, Campagnoli C, Druckmann R, Huber J, Pasqualini JR, Schweppe KW, Thijssen JH. Schindler AE, et al. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16. doi: 10.1016/j.maturitas.2003.09.014. Maturitas. 2003. PMID: 14670641 Review.
Some of the synthetic progestins are prodrugs, which need to be metabolized to become active compounds. Besides the progestogenic effect, which is in common for all progestins, there is a wide range of biological effects, which are different for the various proge …
Some of the synthetic progestins are prodrugs, which need to be metabolized to become active compounds. Besides the progestogenic eff …
Progestins of today and tomorrow.
Liu S, Kciuk O, Frank M, Tyson N. Liu S, et al. Curr Opin Obstet Gynecol. 2022 Dec 1;34(6):344-350. doi: 10.1097/GCO.0000000000000819. Epub 2022 Aug 19. Curr Opin Obstet Gynecol. 2022. PMID: 36036464 Review.
Noncontraceptive use of progestins often overlaps with contraceptive indications, which allows for simultaneous multipurpose progestin use, especially in reproductive-aged patients. More studies are needed to determine contraceptive doses of progestins used f …
Noncontraceptive use of progestins often overlaps with contraceptive indications, which allows for simultaneous multipurpose proge …
Clinical pharmacology of progestins.
Capozzi A, Scambia G, Lello S. Capozzi A, et al. Minerva Obstet Gynecol. 2022 Aug;74(4):364-376. doi: 10.23736/S2724-606X.21.04881-8. Epub 2021 Jun 28. Minerva Obstet Gynecol. 2022. PMID: 34180615 Review.
INTRODUCTION: In this paper, we report general pharmacological profile and major biological activities of natural progesterone (P) and progestins. The aim of this article consists of synthesizing the principal aspects of pharmacology and metabolism of P and progestins …
INTRODUCTION: In this paper, we report general pharmacological profile and major biological activities of natural progesterone (P) and pr …
Progestins and acne vulgaris: a review.
Bosanac SS, Trivedi M, Clark AK, Sivamani RK, Larsen LN. Bosanac SS, et al. Dermatol Online J. 2018 May 15;24(5):13030/qt6wm945xf. Dermatol Online J. 2018. PMID: 30142728 Free article. Review.
The role of exogenous progestin in the development of acne is unclear. Progestins are known for their androgenic potential, but newer generations of progestins have low or anti-androgenic activity. ...Our review demonstrates that the cause and effect relation …
The role of exogenous progestin in the development of acne is unclear. Progestins are known for their androgenic potential, bu …
Progestins.
Hirvonen E. Hirvonen E. Maturitas. 1996 May;23 Suppl:S13-8. doi: 10.1016/0378-5122(96)01005-5. Maturitas. 1996. PMID: 8865133 Review.
However, because progestins may cause both subjective and metabolic adverse effects minimum effective antiproliferative doses are recommended. The duration of the progestin phase cannot be shortened to less than 10 days whereas the frequency of administration appare …
However, because progestins may cause both subjective and metabolic adverse effects minimum effective antiproliferative doses are rec …
Progesterone, progestins and the breast in menopause treatment.
Gompel A, Plu-Bureau G. Gompel A, et al. Climacteric. 2018 Aug;21(4):326-332. doi: 10.1080/13697137.2018.1476483. Epub 2018 Jun 1. Climacteric. 2018. PMID: 29852797 Review.
Different levels of risk with estrogen-only treatment and combined treatment with estrogen + progestin are shown in randomized trials and observational studies. Several non-randomized studies show a lower risk with progesterone and retroprogesterone than with synthetic …
Different levels of risk with estrogen-only treatment and combined treatment with estrogen + progestin are shown in randomized trials …
All progestins are not created equal.
Stanczyk FZ. Stanczyk FZ. Steroids. 2003 Nov;68(10-13):879-90. doi: 10.1016/j.steroids.2003.08.003. Steroids. 2003. PMID: 14667980 Review.
Progestins administered orally undergo extensive hepatic first pass metabolism primarily by reduction and conjugation, and in most instances, relatively high progestin doses are required for therapeutic use. There are limited reliable data on the pharmacokinetics of …
Progestins administered orally undergo extensive hepatic first pass metabolism primarily by reduction and conjugation, and in most in …
Progestins and cancer.
Sitruk-Ware R, Plu-Bureau G. Sitruk-Ware R, et al. Gynecol Endocrinol. 1999 Jun;13 Suppl 4:3-9. doi: 10.1080/gye.13.s4.3.9. Gynecol Endocrinol. 1999. PMID: 12227896 Review.
The role of progestins in breast tissue is less well defined than in the endometrium. ...Finally, striking differences have been observed in progestin use in Europe and in the USA. In France, where the rate of progestin use per head is higher than in the USA, …
The role of progestins in breast tissue is less well defined than in the endometrium. ...Finally, striking differences have been obse …
Pharmacokinetics, metabolism and serum concentrations of progestins used in contraception.
Bick AJ, Louw-du Toit R, Skosana SB, Africander D, Hapgood JP. Bick AJ, et al. Pharmacol Ther. 2021 Jun;222:107789. doi: 10.1016/j.pharmthera.2020.107789. Epub 2020 Dec 13. Pharmacol Ther. 2021. PMID: 33316287 Free PMC article. Review.
These contraceptives differ in the dose and type of synthetic progestogenic compound (progestin) used, as well as the route of administration and whether or not they contain estrogenic compounds. ...This requires a better understanding of the pharmacokinetics, metabolism, …
These contraceptives differ in the dose and type of synthetic progestogenic compound (progestin) used, as well as the route of admini …
What is there to know about the effects of progestins on the human brain and cognition?
Griksiene R, Monciunskaite R, Ruksenas O. Griksiene R, et al. Front Neuroendocrinol. 2022 Oct;67:101032. doi: 10.1016/j.yfrne.2022.101032. Epub 2022 Aug 25. Front Neuroendocrinol. 2022. PMID: 36029852 Review.
Progestins are an important component of hormonal contraceptives (HCs) and hormone replacement therapies (HRTs). Despite an increasing number of studies elucidating the effects of HCs and HRTs, little is known about the effects of different types of progestins inclu …
Progestins are an important component of hormonal contraceptives (HCs) and hormone replacement therapies (HRTs). Despite an increasin …
82,769 results
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