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Year Number of Results
1949 1
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1977 2
1979 2
1981 3
1982 1
1983 1
1985 1
1986 2
1988 1
1989 1
1990 2
1991 2
1992 2
1993 1
1994 1
1995 4
1996 1
1997 3
1998 2
1999 7
2000 10
2001 7
2002 1
2003 3
2004 8
2005 8
2006 9
2007 8
2008 11
2009 14
2010 9
2011 13
2012 17
2013 24
2014 24
2015 28
2016 16
2017 19
2018 24
2019 36
2020 47
2021 46
2022 54
2023 39
2024 24

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474 results

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Page 1
Neohesperidin Protects Angiotensin II-Induced Hypertension and Vascular Remodeling.
Zhang J, Hui Y, Liu F, Yang Q, Lu Y, Chang Y, Liu Q, Ding Y. Zhang J, et al. Front Pharmacol. 2022 May 23;13:890202. doi: 10.3389/fphar.2022.890202. eCollection 2022. Front Pharmacol. 2022. PMID: 35677431 Free PMC article.
Neohesperidin has been studied for a variety of diseases in addition to hypertension. ...Neohesperidin inhibited angiotensin II-induced migration of vascular smooth muscle cells. ...
Neohesperidin has been studied for a variety of diseases in addition to hypertension. ...Neohesperidin inhibited angiotensin I …
Neohesperidin dihydrochalbazone protects against septic acute kidney injury in mice.
Yang R, Qi L, Liang W. Yang R, et al. Phytomedicine. 2023 Feb;110:154623. doi: 10.1016/j.phymed.2022.154623. Epub 2022 Dec 25. Phytomedicine. 2023. PMID: 36608504
BACKGROUND: Neohesperidin dihydrochalbazone (NHDC) shows a range of pharmacological actions, however, in septic acute kidney injury (AKI), the effect of NHDC is little known. ...
BACKGROUND: Neohesperidin dihydrochalbazone (NHDC) shows a range of pharmacological actions, however, in septic acute kidney injury ( …
Therapeutic Effects of Citrus Flavonoids Neohesperidin, Hesperidin and Its Aglycone, Hesperetin on Bone Health.
Ortiz AC, Fideles SOM, Reis CHB, Bellini MZ, Pereira ESBM, Pilon JPG, de Marchi MÂ, Detregiachi CRP, Flato UAP, Trazzi BFM, Pagani BT, Ponce JB, Gardizani TP, Veronez FS, Buchaim DV, Buchaim RL. Ortiz AC, et al. Biomolecules. 2022 Apr 23;12(5):626. doi: 10.3390/biom12050626. Biomolecules. 2022. PMID: 35625554 Free PMC article. Review.
Neohesperidin, in the form of neohesperidin dihydrochalcone (NHDC), also has dietary properties as a sweetener. ...In this literature review, we compiled studies that investigated the effects of neohesperidin, hesperidin and its aglycone, hesperetin, on bone …
Neohesperidin, in the form of neohesperidin dihydrochalcone (NHDC), also has dietary properties as a sweetener. ...In this lit …
The Effect of Artificial Sweeteners Use on Sweet Taste Perception and Weight Loss Efficacy: A Review.
Wilk K, Korytek W, Pelczyńska M, Moszak M, Bogdański P. Wilk K, et al. Nutrients. 2022 Mar 16;14(6):1261. doi: 10.3390/nu14061261. Nutrients. 2022. PMID: 35334918 Free PMC article. Review.
NNS include aspartame, acesulfame-K, sucralose, saccharin, cyclamate, neohesperidin dihydrochalcone (neohesperidin DC), neotame, taumatin, and advantame. ...
NNS include aspartame, acesulfame-K, sucralose, saccharin, cyclamate, neohesperidin dihydrochalcone (neohesperidin DC), neotam …
Neohesperidin Dihydrochalcone Ameliorates High-Fat Diet-Induced Glycolipid Metabolism Disorder in Rats.
Xiao Y, Su D, Hu X, Yang G, Shan Y. Xiao Y, et al. J Agric Food Chem. 2022 Aug 3;70(30):9421-9431. doi: 10.1021/acs.jafc.2c03574. Epub 2022 Jul 21. J Agric Food Chem. 2022. PMID: 35862634
High-fat diet (HFD) is closely related to the formation of metabolic diseases. Studies have confirmed that neohesperidin dihydrochalcone (NHDC) possesses the biological activity of preventing glycolipid metabolism disorder. ...
High-fat diet (HFD) is closely related to the formation of metabolic diseases. Studies have confirmed that neohesperidin dihydrochalc …
Neohesperidin and spike RBD interaction in omicron and its sub-variants: In silico, structural and simulation studies.
Singh JK, Dubey S, Srivastava G, Siddiqi MI, Srivastava SK. Singh JK, et al. Comput Biol Med. 2023 Jan;152:106392. doi: 10.1016/j.compbiomed.2022.106392. Epub 2022 Dec 5. Comput Biol Med. 2023. PMID: 36502697 Free PMC article.
Free energy binding analyses further validates that neohesperidin forms a stable complex with spike RBD in omicron and BA.2 with a binding energy of -237.9 18.7 kJ/mol and -164.1 17.5 kJ/mol respectively. Key residual differences in the RBD interface of these variants form …
Free energy binding analyses further validates that neohesperidin forms a stable complex with spike RBD in omicron and BA.2 with a bi …
Neohesperidin promotes the proliferation and osteogenic differentiation of BMSCs via BMP2-Wnt/beta-catenin pathway.
Yuan S, Zhang C, Wang B. Yuan S, et al. Cell Cycle. 2022 Jan;21(2):187-201. doi: 10.1080/15384101.2021.2015668. Epub 2021 Dec 17. Cell Cycle. 2022. PMID: 34919014 Free PMC article.
The present study aimed to investigate the role of neohesperidin (NH) in mice with steroid-induced femoral head necrosis (SONFH) and in bone marrow stromal cells (BMSCs). ...
The present study aimed to investigate the role of neohesperidin (NH) in mice with steroid-induced femoral head necrosis (SONFH) and …
Neohesperidin suppresses IgE-mediated anaphylactic reactions and mast cell activation via Lyn-PLC-Ca(2+) pathway.
Zhao T, Hu S, Ma P, Che D, Liu R, Zhang Y, Wang J, Li C, Ding Y, Fu J, An H, Gao Z, Zhang T. Zhao T, et al. Phytother Res. 2019 Aug;33(8):2034-2043. doi: 10.1002/ptr.6385. Epub 2019 Jun 14. Phytother Res. 2019. PMID: 31197891
In this study, the anti-allergic and anti-inflammatory potentials of neohesperidin were investigated along with its molecular mechanism. The anti-anaphylactic activity of neohesperidin was evaluated through hind paw extravasation study in mice. ...Neohesperidin …
In this study, the anti-allergic and anti-inflammatory potentials of neohesperidin were investigated along with its molecular mechani …
Neohesperidin Induces Cell Cycle Arrest, Apoptosis, and Autophagy via the ROS/JNK Signaling Pathway in Human Osteosarcoma Cells.
Wang S, Li Z, Liu W, Wei G, Yu N, Ji G. Wang S, et al. Am J Chin Med. 2021;49(5):1251-1274. doi: 10.1142/S0192415X21500609. Epub 2021 Jun 2. Am J Chin Med. 2021. PMID: 34107857
The formation of autophagosomes indicated that autophagy occurred in neohesperidin-treated cells and the apoptotic effect of neohesperidin was significantly increased after the use of autophagy inhibitors. ...Moreover, neohesperidin induced activation of the …
The formation of autophagosomes indicated that autophagy occurred in neohesperidin-treated cells and the apoptotic effect of neohe …
Neohesperidin prevents colorectal tumorigenesis by altering the gut microbiota.
Gong Y, Dong R, Gao X, Li J, Jiang L, Zheng J, Cui S, Ying M, Yang B, Cao J, He Q. Gong Y, et al. Pharmacol Res. 2019 Oct;148:104460. doi: 10.1016/j.phrs.2019.104460. Epub 2019 Sep 24. Pharmacol Res. 2019. PMID: 31560944
Neohesperidin (NHP), derived from citrus fruits, has attracted considerable interest due to its preventative and therapeutic effects on numerous diseases. ...
Neohesperidin (NHP), derived from citrus fruits, has attracted considerable interest due to its preventative and therapeutic effects …
474 results