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1987 1
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Napyradiomycin B4 Suppresses RANKL-Induced Osteoclastogenesis and Prevents Alveolar Bone Destruction in Experimental Periodontitis.
Kim JA, Lim S, Kim GJ, Silviani V, Kim JE, Bae JS, Nam JW, Choi H, Park EK. Kim JA, et al. ACS Pharmacol Transl Sci. 2024 Apr 3;7(4):1023-1031. doi: 10.1021/acsptsci.3c00315. eCollection 2024 Apr 12. ACS Pharmacol Transl Sci. 2024. PMID: 38633588
Phosphorylation levels of signaling proteins were assessed by immunoblot analysis to understand the molecular action of napyradiomycin B4. The in vivo efficacy of napyradiomycin B4 was examined under experimental periodontitis, and alveolar bone destru …
Phosphorylation levels of signaling proteins were assessed by immunoblot analysis to understand the molecular action of napyradiomycin …
New antibiotic napyradiomycins A2 and B4 and stereochemistry of napyradiomycins.
Shiomi K, Nakamura H, Iinuma H, Naganawa H, Takeuchi T, Umezawa H, Iitaka Y. Shiomi K, et al. J Antibiot (Tokyo). 1987 Sep;40(9):1213-9. doi: 10.7164/antibiotics.40.1213. J Antibiot (Tokyo). 1987. PMID: 3680038 Free article.
The structure of napyradiomycin A2 was elucidated as 16-hydroxy-17-methylenenapyradiomycin A1 by NMR studies. The absolute structure of napyradiomycin B4 was determined as 13-hydroxy-13-methylnapyradiomycin B1 by X-ray crystallography and therefore the configuration …
The structure of napyradiomycin A2 was elucidated as 16-hydroxy-17-methylenenapyradiomycin A1 by NMR studies. The absolute structure of n …