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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1970 1
1971 1
1972 3
1973 4
1974 8
1975 9
1976 6
1977 10
1978 3
1979 5
1980 6
1981 3
1982 4
1983 7
1984 9
1985 6
1986 12
1987 7
1988 15
1989 12
1990 16
1991 13
1992 12
1993 15
1994 12
1995 16
1996 15
1997 8
1998 15
1999 12
2000 14
2001 6
2002 4
2003 4
2004 1
2005 1
2006 2
2007 2
2008 1
2009 2
2014 1
2015 1
2024 0

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304 results

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Page 1
Nafenopin.
[No authors listed] [No authors listed] IARC Monogr Eval Carcinog Risk Chem Hum. 1980;24:125-33. IARC Monogr Eval Carcinog Risk Chem Hum. 1980. PMID: 7009388 Review. No abstract available.
Cytosolic epoxide hydrolase.
Meijer J, DePierre JW. Meijer J, et al. Chem Biol Interact. 1988;64(3):207-49. doi: 10.1016/0009-2797(88)90100-7. Chem Biol Interact. 1988. PMID: 3277731 Review.
The only xenobiotics presently known to induce cytosolic epoxide hydrolase are substances which also cause peroxisome proliferation, e.g., clofibrate, nafenopin and phthalate esters. These and other observations indicate that this enzyme may actually be localized in peroxi …
The only xenobiotics presently known to induce cytosolic epoxide hydrolase are substances which also cause peroxisome proliferation, e.g., c …
Hypolipidemic drugs.
Sirtori C, Fumagalli R, Paoletti R. Sirtori C, et al. Adv Exp Med Biol. 1973;38:171-98. Adv Exp Med Biol. 1973. PMID: 4594063 Review. No abstract available.
Fatty acid activation of peroxisome proliferator-activated receptor (PPAR).
Bocos C, Göttlicher M, Gearing K, Banner C, Enmark E, Teboul M, Crickmore A, Gustafsson JA. Bocos C, et al. J Steroid Biochem Mol Biol. 1995 Jun;53(1-6):467-73. doi: 10.1016/0960-0760(95)00093-f. J Steroid Biochem Mol Biol. 1995. PMID: 7626496 Review.
Peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643 have been shown to activate peroxisome proliferator-activated receptor (PPAR), a member of the steroid nuclear receptor superfamily. ...
Peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643 have been shown to activate peroxisome proliferator-activat …
Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis.
James NH, Roberts RA. James NH, et al. Carcinogenesis. 1996 Aug;17(8):1623-32. doi: 10.1093/carcin/17.8.1623. Carcinogenesis. 1996. PMID: 8761418
Here we describe the ability of nafenopin to suppress apoptosis in mouse, hamster, guinea pig and rat hepatocytes and induce S-phase in mouse and rat hepatocytes. ...Thus, all the species examined responded to nafenopin by a suppression of both spontaneous and TGF b …
Here we describe the ability of nafenopin to suppress apoptosis in mouse, hamster, guinea pig and rat hepatocytes and induce S-phase …
PPAR alpha and the regulation of cell division and apoptosis.
Roberts RA, Chevalier S, Hasmall SC, James NH, Cosulich SC, Macdonald N. Roberts RA, et al. Toxicology. 2002 Dec 27;181-182:167-70. doi: 10.1016/s0300-483x(02)00275-5. Toxicology. 2002. PMID: 12505304 Review.
Peroxisome proliferators (PPs) such as the hypolipidaemic drug, nafenopin and the phthalate plasticiser 2-diethylhexylphthalate induce rodent hepatocyte cell proliferation and suppress apoptosis leading to tumours. ...
Peroxisome proliferators (PPs) such as the hypolipidaemic drug, nafenopin and the phthalate plasticiser 2-diethylhexylphthalate induc …
Role of apoptosis for mouse liver growth regulation and tumor promotion: comparative analysis of mice with high (C3H/He) and low (C57Bl/6J) cancer susceptibility.
Bursch W, Grasl-Kraupp B, Wastl U, Hufnagl K, Chabicovsky M, Taper H, Schulte-Hermann R. Bursch W, et al. Toxicol Lett. 2004 Apr 1;149(1-3):25-35. doi: 10.1016/j.toxlet.2003.12.018. Toxicol Lett. 2004. PMID: 15093245 Review.
First, in short-term in vivo experiments (7-21 days), mouse liver growth (C3H/He, C57BL/6J) was induced by administration of phenobarbital (PB; 2 days 500 ppm + 5 days 750 ppm via the food) or nafenopin (NAF; 7 days 500 ppm via the food), cessation of PB or NAF treatment s …
First, in short-term in vivo experiments (7-21 days), mouse liver growth (C3H/He, C57BL/6J) was induced by administration of phenobarbital ( …
Regulation of CYP2C11 by dehydroepiandrosterone and peroxisome proliferators: identification of the negative regulatory region of the gene.
Ripp SL, Falkner KC, Pendleton ML, Tamasi V, Prough RA. Ripp SL, et al. Mol Pharmacol. 2003 Jul;64(1):113-22. doi: 10.1124/mol.64.1.113. Mol Pharmacol. 2003. PMID: 12815167
A mutation at -121 bp significantly diminished basal expression of CYP2C11 but did not affect negative regulation by DHEA or nafenopin. A mutation at -75 bp had only a small effect on basal expression but completely abolished negative regulation by DHEA and nafenopin
A mutation at -121 bp significantly diminished basal expression of CYP2C11 but did not affect negative regulation by DHEA or nafenopin
No measurable increase in thymidine glycol or 8-hydroxydeoxyguanosine in liver DNA of rats treated with nafenopin or choline-devoid low-methionine diet.
Hegi ME, Ulrich D, Sagelsdorff P, Richter C, Lutz WK. Hegi ME, et al. Mutat Res. 1990 May;238(3):325-9. doi: 10.1016/0165-1110(90)90025-7. Mutat Res. 1990. PMID: 2342515 Free article.
Male rats were treated for 2 months with 1000 ppm nafenopin in the diet or for 4 or 7 days with a choline-devoid low-methionine diet. ...
Male rats were treated for 2 months with 1000 ppm nafenopin in the diet or for 4 or 7 days with a choline-devoid low-methionine diet. …
304 results