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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 2
1952 1
1953 1
1965 1
1971 1
1974 2
1975 4
1976 1
1977 1
1979 3
1980 3
1981 3
1982 6
1983 2
1984 7
1985 4
1986 4
1987 2
1988 4
1989 2
1993 3
1994 1
1995 4
1996 3
1998 5
1999 2
2000 2
2001 1
2002 6
2003 3
2004 5
2005 3
2006 1
2007 2
2008 1
2009 2
2010 3
2011 3
2012 2
2013 2
2014 5
2015 4
2016 1
2017 2
2018 2
2019 3
2020 1
2021 1
2022 3
2023 4
2024 3

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130 results

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Page 1
Metabolic and Metabo-Clinical Signatures of Type 2 Diabetes, Obesity, Retinopathy, and Dyslipidemia.
Yousri NA, Suhre K, Yassin E, Al-Shakaki A, Robay A, Elshafei M, Chidiac O, Hunt SC, Crystal RG, Fakhro KA. Yousri NA, et al. Diabetes. 2022 Feb 1;71(2):184-205. doi: 10.2337/db21-0490. Diabetes. 2022. PMID: 34732537 Free PMC article.
These signatures revealed metabolic pathways associated with different clinical patterns and identified patients with extreme (very high/low) clinical variables associated with extreme metabolite levels in specific pathways. Among our novel findings are the role of N-ac
These signatures revealed metabolic pathways associated with different clinical patterns and identified patients with extreme (very high/low …
N-Acetylglutamate and N-acetylmethionine compromise mitochondrial bioenergetics homeostasis and glutamate oxidation in brain of developing rats: Potential implications for the pathogenesis of ACY1 deficiency.
Bortoluzzi VT, Ribeiro RT, Pinheiro CV, Castro ET, Tavares TQ, Leipnitz G, Sass JO, Castilho RF, Amaral AU, Wajner M. Bortoluzzi VT, et al. Biochem Biophys Res Commun. 2023 Dec 3;684:149123. doi: 10.1016/j.bbrc.2023.149123. Epub 2023 Oct 17. Biochem Biophys Res Commun. 2023. PMID: 37871522
Considering that the pathogenesis of ACY1 is practically unknown and the brain is highly dependent on energy production, the in vitro effects of N-acetylglutamate (NAG) and N-acetylmethionine (NAM), major metabolites accumulating in ACY1 deficiency, on the enzyme ac …
Considering that the pathogenesis of ACY1 is practically unknown and the brain is highly dependent on energy production, the in vitro effect …
PANCREATIC LESIONS BY N-ACETYLMETHIONINE.
ALVIZOURI M, VAZQUEZ H, MACOUZET J, CORTES J. ALVIZOURI M, et al. Arch Surg. 1965 Jan;90:11-6. doi: 10.1001/archsurg.1965.01320070013003. Arch Surg. 1965. PMID: 14220627 No abstract available.
Efficacy of the D- and L-isomers of N-acetylmethionine for chicks fed diets containing either crystalline amino acids or intact protein.
Baker DH. Baker DH. J Nutr. 1979 Jun;109(6):970-4. doi: 10.1093/jn/109.6.970. J Nutr. 1979. PMID: 448454
Chick growth assays were used to evaluate the efficacy and toxicity of the L- and D-isomers of N-acetylmethionine when fed as a source of methionine in crystalline amino acid diets. ...
Chick growth assays were used to evaluate the efficacy and toxicity of the L- and D-isomers of N-acetylmethionine when fed as …
Disturbance of mitochondrial functions caused by N-acetylglutamate and N-acetylmethionine in brain of adolescent rats: Potential relevance in aminoacylase 1 deficiency.
Bortoluzzi VT, Ribeiro RT, Zemniaçak ÂB, Cunha SA, Sass JO, Castilho RF, Amaral AU, Wajner M. Bortoluzzi VT, et al. Neurochem Int. 2023 Dec;171:105631. doi: 10.1016/j.neuint.2023.105631. Epub 2023 Oct 16. Neurochem Int. 2023. PMID: 37852579
Considering that the pathological mechanisms of brain damage in this disorder remain mostly unknown, here we investigated whether major metabolites accumulating in ACY1 deficiency, namely N-acetylglutamate (NAG) and N-acetylmethionine (NAM), could be toxic to the br …
Considering that the pathological mechanisms of brain damage in this disorder remain mostly unknown, here we investigated whether major meta …
Large-Scale Metabolomics and the Incidence of Cardiovascular Disease.
Lind L, Fall T, Ärnlöv J, Elmståhl S, Sundström J. Lind L, et al. J Am Heart Assoc. 2023 Jan 17;12(2):e026885. doi: 10.1161/JAHA.122.026885. Epub 2023 Jan 16. J Am Heart Assoc. 2023. PMID: 36645074 Free PMC article.
These metabolites belonged to multiple biochemical classes, such as amino acids, lipids, and nucleotides. Top findings were dimethylglycine and N-acetylmethionine. A lasso selection of 5 metabolites improved discrimination when added on top of traditional CVD risk f …
These metabolites belonged to multiple biochemical classes, such as amino acids, lipids, and nucleotides. Top findings were dimethylglycine …
Comparison of N-acetylmethionine reactivity between oxaliplatin and an oxaliplatin derivative with chiral (S,S) amine nitrogen atoms.
Williams KM, Poynter AD, Hendrie JD, Jackson DC, Martin VK. Williams KM, et al. Inorganica Chim Acta. 2013 May 24;401:64-69. doi: 10.1016/j.ica.2013.03.008. Inorganica Chim Acta. 2013. PMID: 23626375 Free PMC article.
The complex (S,R,R,S)-Pt(Me(2)dach)(oxalate), where S,R,R,S represents the chiralities at N,C,C,N, respectively, was prepared and characterized by (1)H NMR spectroscopy, COSY, NOESY, and HMQC. Oxaliplatin reacts with N-acetylmethionine (N-AcMet) to form [Pt(dach)(N- …
The complex (S,R,R,S)-Pt(Me(2)dach)(oxalate), where S,R,R,S represents the chiralities at N,C,C,N, respectively, was prepared and characteri …
In vitro metabolism of ethionine, N-acetyl-ethionine and N-acetylmethionine by rat liver microsomes.
Francis KT, Smith RC. Francis KT, et al. Experientia. 1975 Aug 15;31(8):890-1. doi: 10.1007/BF02358833. Experientia. 1975. PMID: 1157846
Rat liver microsomes deacetylated N-acetylethionine and N-acetyl-methionine to ethionine and methionine. The deacetylation of N-acetylmethionine was more rapid than the deacetylation of N-acetylethionine. Ethionine was slowly converted to ethionine sulfoxide by the …
Rat liver microsomes deacetylated N-acetylethionine and N-acetyl-methionine to ethionine and methionine. The deacetylation of N-ac
Model sclerotization studies. 4. Generation of N-acetylmethionyl catechol adducts during tyrosinase-catalyzed oxidation of catechols in the presence of N-acetylmethionine.
Sugumaran M, Nelson E. Sugumaran M, et al. Arch Insect Biochem Physiol. 1998;38(1):44-52. doi: 10.1002/(SICI)1520-6327(1998)38:1<44::AID-ARCH5>3.0.CO;2-V. Arch Insect Biochem Physiol. 1998. PMID: 9589603
Incubation of catechol with mushroom tyrosinase in the presence of N-acetylmethionine resulted in the generation of an adduct. This product was identified to be N-acetylmethionyl catechol, on the basis of spectral characteristics and well-characterized chemical reac …
Incubation of catechol with mushroom tyrosinase in the presence of N-acetylmethionine resulted in the generation of an adduct. …
Associations of cord blood metabolites with early childhood obesity risk.
Isganaitis E, Rifas-Shiman SL, Oken E, Dreyfuss JM, Gall W, Gillman MW, Patti ME. Isganaitis E, et al. Int J Obes (Lond). 2015 Jul;39(7):1041-8. doi: 10.1038/ijo.2015.39. Epub 2015 Mar 25. Int J Obes (Lond). 2015. PMID: 25804930 Free PMC article.
Three metabolites were related to tryptophan: serotonin, tryptophan betaine and tryptophyl leucine (46%, 48% and 26% lower in cases, respectively, P<0.05). Mean levels of two methyl donors, dimethylglycine and N-acetylmethionine, were also lower in cases (18% and …
Three metabolites were related to tryptophan: serotonin, tryptophan betaine and tryptophyl leucine (46%, 48% and 26% lower in cases, respect …
130 results