Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1980 2
1982 2
1983 1
1984 1
1985 1
1986 2
1989 3
1991 1
1993 1
1994 1
2008 1
2012 1
2016 1
2019 1
2022 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

21 results

Results by year

Filters applied: . Clear all
Page 1
The pharmacokinetics of dl- and l-moprolol in the human.
Harvengt C, Desager JP. Harvengt C, et al. Int J Clin Pharmacol Ther Toxicol. 1982 Feb;20(2):57-61. Int J Clin Pharmacol Ther Toxicol. 1982. PMID: 6120901
The pharmacokinetics of a single dose (75 mg) of dl-moprolol and l-moprolol, a new beta -blocking agent, were appraised over 3 days in two groups of ten volunteers. ...The double product (systolic blood pressure x heart rate) was significantly decreased only in volu …
The pharmacokinetics of a single dose (75 mg) of dl-moprolol and l-moprolol, a new beta -blocking agent, were appraised over 3 …
Development of a novel chemoenzymatic route to enantiomerically enriched beta-adrenolytic agents. A case study toward propranolol, alprenolol, pindolol, carazolol, moprolol, and metoprolol.
Borowiecki P, Zdun B, Popow N, Wiklińska M, Reiter T, Kroutil W. Borowiecki P, et al. RSC Adv. 2022 Aug 10;12(34):22150-22160. doi: 10.1039/d2ra04302e. eCollection 2022 Aug 4. RSC Adv. 2022. PMID: 36043081 Free PMC article.
The enantiopure (R)-chlorohydrin (>99% ee) subsequently obtained was used for the synthesis of a series of model (R)-(+)-beta-blockers (i.e., propranolol, alprenolol, pindolol, carazolol, moprolol, and metoprolol), which were produced with enantiomeric excess in the ran …
The enantiopure (R)-chlorohydrin (>99% ee) subsequently obtained was used for the synthesis of a series of model (R)-(+)-beta-blockers (i …
Chemoenzymatic Route for the Synthesis of (S)-Moprolol, a Potential beta-Blocker.
Ghosh S, Bhaumik J, Banoth L, Banesh S, Banerjee UC. Ghosh S, et al. Chirality. 2016 Apr;28(4):313-8. doi: 10.1002/chir.22574. Epub 2016 Jan 28. Chirality. 2016. PMID: 26821612
A biocatalytic route for the synthesis of a potential beta-blocker, (S)-moprolol is reported here. Enantiopure synthesis of moprolol is mainly dependent on the chiral intermediate, 3-(2-methoxyphenoxy)-propane-1,2-diol. ...Further, the enantiopure intermediate was u …
A biocatalytic route for the synthesis of a potential beta-blocker, (S)-moprolol is reported here. Enantiopure synthesis of moprol …
Identification and determination of the enantiomers of moprolol and their metabolites in human urine by high-performance liquid chromatography and gas chromatography-mass spectrometry.
Li F, Bi H, Côté M, Cooper S. Li F, et al. J Chromatogr. 1993 Dec 22;622(2):187-95. doi: 10.1016/0378-4347(93)80265-6. J Chromatogr. 1993. PMID: 7908669
The coefficients of variation (C.V.) were less than 3.2 and 6.5% for intra- and inter-assays, respectively. Moprolol could be detected in urine up to 24 h after oral administration of a 50-mg dose of moprolol. Unconjugated and conjugated enantiomers of moprolol …
The coefficients of variation (C.V.) were less than 3.2 and 6.5% for intra- and inter-assays, respectively. Moprolol could be detecte …
Ketoreductase catalyzed stereoselective bioreduction of α-nitro ketones.
Wang Z, Wu X, Li Z, Huang Z, Chen F. Wang Z, et al. Org Biomol Chem. 2019 Apr 3;17(14):3575-3580. doi: 10.1039/c9ob00051h. Org Biomol Chem. 2019. PMID: 30900703
Select beta-nitro alcohols, including the synthetic intermediates of bioactive molecules (R)-tembamide, (S)-tembamide, (S)-moprolol, (S)-toliprolol and (S)-propanolol, were stereoselectively synthesized in preparative scale with 42% to 90% isolated yields, showcasing the p …
Select beta-nitro alcohols, including the synthetic intermediates of bioactive molecules (R)-tembamide, (S)-tembamide, (S)-moprolol, …
Electrophysiological evaluation of the beta-blocking properties and direct membrane effects of l-moprolol and its enantiomer d-moprolol.
Porciatti F, Cerbai E, Masini I, Mugelli A. Porciatti F, et al. Arch Int Pharmacodyn Ther. 1989 May-Jun;299:200-9. Arch Int Pharmacodyn Ther. 1989. PMID: 2570555
The electrophysiological and beta-blocking properties of l- and d-moprolol have been studied in sheep cardiac Purkinje fibers. l-Moprolol (0.3-100 nM) dose-dependently antagonized the inotropic (ED50 = 1.2 +/- 0.4 nM) and chronotropic (ED50 = 5.8 +/- 0.6 nM) effects …
The electrophysiological and beta-blocking properties of l- and d-moprolol have been studied in sheep cardiac Purkinje fibers. l-M …
The efficacy of the combination of l-moprolol and dipivefrin in reducing the intraocular pressure in primary open-angle glaucoma or in ocular hypertension.
Rossetti L, Barbieri P, Velati P, Bujtar E, Orzalesi N. Rossetti L, et al. Graefes Arch Clin Exp Ophthalmol. 1994 Nov;232(11):670-4. doi: 10.1007/BF00171382. Graefes Arch Clin Exp Ophthalmol. 1994. PMID: 7843592 Clinical Trial.
RESULTS: The results of this study indicated that l-moprolol and dipivefrin had an equivalent effect in lowering the intraocular pressure. ...CONCLUSION: This trial demonstrated that the combination of l-moprolol and dipivefrin is an effective and safe treatment for …
RESULTS: The results of this study indicated that l-moprolol and dipivefrin had an equivalent effect in lowering the intraocular pres …
Synthesis and pharmacological study of a thiophene analogue of moprolol and related compounds.
el-Ashmawy MB, Lissavetzky J, Darias V, Martín-Herrera D. el-Ashmawy MB, et al. Arch Pharm (Weinheim). 1991 Jan;324(1):45-8. doi: 10.1002/ardp.19913240112. Arch Pharm (Weinheim). 1991. PMID: 1675047
The syntheses of the thiophenic analogue of Moprolol (1d) and of its related compound 1a are described. From a preliminary pharmacological evaluation compound 1d seems worthy of further studies due to its notable beta-blocking activity and its remarkable anti-platelet aggr …
The syntheses of the thiophenic analogue of Moprolol (1d) and of its related compound 1a are described. From a preliminary pharmacolo …
21 results