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Page 1
Promising new agents for treatment of patients with colorectal cancer.
Von Hoff DD. Von Hoff DD. Semin Oncol. 1998 Oct;25(5 Suppl 11):47-52. Semin Oncol. 1998. PMID: 9786316 Review.
In addition, other agents have shown promising preclinical activity against the disease: 6-hydroxymethylacylfulvene (HMAF; MGI 114), LY 295501, bizelesin (U-7779; NSC615291), and ONYX-015. Finally, several agents may prevent colorectal cancer through prevention of t …
In addition, other agents have shown promising preclinical activity against the disease: 6-hydroxymethylacylfulvene (HMAF; MGI 114), LY
FLAG epitope positioned in an external loop preserves normal biophysical properties of CFTR.
Schultz BD, Takahashi A, Liu C, Frizzell RA, Howard M. Schultz BD, et al. Am J Physiol. 1997 Dec;273(6):C2080-9. doi: 10.1152/ajpcell.1997.273.6.C2080. Am J Physiol. 1997. PMID: 9435515
Channel conductance in symmetric Cl- (11.2 pS), anion permeability ratio (1.66), and block by gluconate indicate that the anion conduction pathway is indistinguishable from wtCFTR. Sulfonylureas (glibenclamide and LY-295501) inhibited M2-901/ CFTR channel activity b …
Channel conductance in symmetric Cl- (11.2 pS), anion permeability ratio (1.66), and block by gluconate indicate that the anion conduction p …
Antitumor diarylsulfonylureas: novel agents with unfulfilled promise.
Houghton PJ, Houghton JA. Houghton PJ, et al. Invest New Drugs. 1996;14(3):271-80. doi: 10.1007/BF00194530. Invest New Drugs. 1996. PMID: 8958182 Review.
Here we review the activity of sulofenur and a second generation diarylsulfonylurea, LY295501 N-[5-(2, 3-dihydrobenzofuryl) sulfonyl]-N'-(3,4-dichlorophenyl)urea, against colon tumor xenografts, and some …
Here we review the activity of sulofenur and a second generation diarylsulfonylurea, LY295501 N-[5-(2, 3-dihy
Efficacy of sulofenur and a second generation diarylsulfonylurea, N-[5-(2,3-dihydrobenzofuryl)sulfonyl]-N'-(3,4-dichlorophenyl)urea (LY295501), against colon adenocarcinoma xenografts.
Houghton PJ, Cheshire PJ, Myers L, Lutz L, Toth J, Grindey GB, Houghton JA. Houghton PJ, et al. Anticancer Drugs. 1995 Apr;6(2):317-23. doi: 10.1097/00001813-199504000-00017. Anticancer Drugs. 1995. PMID: 7795279
Sulofenur and a second generation diarylsulfonylurea (DSU), N-[5-(2,3-dihydrobenzofuryl)sulfonyl]-N'-(3,4-dichlorophenyl)urea (LY295501), were evaluated against a panel of eight colon adenocarcinoma xeno …
Sulofenur and a second generation diarylsulfonylurea (DSU), N-[5-(2,3-dihydrobenzofuryl)sulfonyl]- …