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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1957 1
1978 2
1979 3
1980 6
1981 13
1982 20
1983 17
1984 24
1985 41
1986 97
1987 129
1988 203
1989 233
1990 281
1991 373
1992 376
1993 363
1994 369
1995 421
1996 382
1997 356
1998 332
1999 327
2000 334
2001 307
2002 286
2003 268
2004 255
2005 264
2006 245
2007 231
2008 223
2009 215
2010 164
2011 181
2012 180
2013 191
2014 167
2015 148
2016 137
2017 142
2018 149
2019 134
2020 130
2021 110
2022 93
2023 101
2024 35

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8,597 results

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Page 1
Blockade of IL-11 Trans-Signaling or JAK2/STAT3 Signaling Ameliorates the Profibrotic Effect of IL-11.
Ye W, Wang Q, Zhao L, Wang C, Zhang D, Zhou M, Chen F, Wang W, Zhu Z, Guo W, Liu Y, Zou H, Xue Y. Ye W, et al. Immunol Invest. 2023 Nov;52(6):703-716. doi: 10.1080/08820139.2023.2222746. Epub 2023 Jul 4. Immunol Invest. 2023. PMID: 37401665
METHODS: Plasma IL-11 level was evaluated in 32 patients with SSc and 15 healthy controls, while the expression levels of ADAM10, ADAM17, IL-11, IL-11 Ralpha, or IL-11 co-stained with CD3 or CD163 in the skin of SSc patients and healthy controls were analyzed. Fibroblasts were tr …
METHODS: Plasma IL-11 level was evaluated in 32 patients with SSc and 15 healthy controls, while the expression levels of ADAM10, ADAM17, IL …
Artificial oocyte activation with ionomycin compared with A23187 among patients at risk of failed or impaired fertilization.
Jia L, Chen P, Su W, He S, Guo Y, Zheng L, Fang C, Liang X. Jia L, et al. Reprod Biomed Online. 2023 Jan;46(1):35-45. doi: 10.1016/j.rbmo.2022.08.105. Epub 2022 Aug 25. Reprod Biomed Online. 2023. PMID: 36379856
Couples and underwent 171 ICSI-AOA cycles using either 10 mol/l ionomycin or commercial A23187. The embryological and clinical outcomes were compared. ...AOA with ionomycin significantly increased the day 3 cleavage rate (P = 0.009) when compared with A23187 in the …
Couples and underwent 171 ICSI-AOA cycles using either 10 mol/l ionomycin or commercial A23187. The embryological and clinical outcom …
The formation constants of ionomycin with divalent cations in 80% methanol/water.
Stiles MK, Craig ME, Gunnell SL, Pfeiffer DR, Taylor RW. Stiles MK, et al. J Biol Chem. 1991 May 5;266(13):8336-42. J Biol Chem. 1991. PMID: 1850743 Free article.
The protonation constants and complex formation constants of ionomycin have been determined in 80% methanol/water (w/w) at 25.0 degrees C and mu = 0.050 (tetraethylammonium perchlorate). ...The pH dependence of the values of KMI' indicated that 1:1 divalent metal ion-io …
The protonation constants and complex formation constants of ionomycin have been determined in 80% methanol/water (w/w) at 25.0 degre …
PLCζ can stably regulate Ca2+ fluctuations in early embryo.
Yuan LM, Chen YL, Shi XH, Wu XX, Liu XJ, Liu SP, Chen N, Sai WJ. Yuan LM, et al. Theriogenology. 2022 Oct 1;191:16-21. doi: 10.1016/j.theriogenology.2022.06.018. Epub 2022 Jun 21. Theriogenology. 2022. PMID: 35939900
The results demonstrated that both the PLCzeta and ionomycin combined with 6-DMAP activation methods induced sheep oocyte parthenogenetic activation and development in early embryos. In comparisons, the cleavage rate of ionomycin combined with 6-DMAP activation was …
The results demonstrated that both the PLCzeta and ionomycin combined with 6-DMAP activation methods induced sheep oocyte parthenogen …
Development of prepubertal goat oocytes after their in vitro maturation and chemical activation.
Hong S, Vettical BS, Wani NA. Hong S, et al. Zygote. 2020 Dec;28(6):447-452. doi: 10.1017/S0967199420000313. Epub 2020 Aug 10. Zygote. 2020. PMID: 32772939
In Experiment 2, mature oocytes were activated with either 5 M ionomycin or 7% ethanol. After 18 h, some oocytes were randomly fixed and stained to evaluate their chromatin status, while others were cultured in embryo culture medium to study their further development. ...T …
In Experiment 2, mature oocytes were activated with either 5 M ionomycin or 7% ethanol. After 18 h, some oocytes were randomly fixed …
Culture conditions affect Ca2+ release in artificially activated mouse and human oocytes.
Lu Y, Bonte D, Ferrer-Buitrago M, Popovic M, Neupane J, Van der Jeught M, Leybaert L, De Sutter P, Heindryckx B. Lu Y, et al. Reprod Fertil Dev. 2018 Jun;30(7):991-1001. doi: 10.1071/RD17145. Reprod Fertil Dev. 2018. PMID: 29325603
Using both mouse and human oocytes, in the present study we investigated the effects of ionomycin and Ca2+ concentrations on the pattern of Ca2+ release and embryonic developmental potential. In the mouse, application of 5muM ionomycin in potassium simplex optimisat …
Using both mouse and human oocytes, in the present study we investigated the effects of ionomycin and Ca2+ concentrations on the patt …
Citrullination of actin-ligand and nuclear structural proteins, cytoskeleton reorganization and protein redistribution across cellular fractions are early events in ionomycin-induced NETosis.
Reis LR, Souza Junior DR, Tomasin R, Bruni-Cardoso A, Di Mascio P, Ronsein GE. Reis LR, et al. Redox Biol. 2023 Aug;64:102784. doi: 10.1016/j.redox.2023.102784. Epub 2023 Jun 19. Redox Biol. 2023. PMID: 37356135 Free PMC article.
Here we use live-imaging microscopy and proteomic studies of the neutrophil cellular fractions to investigate the early events in ionomycin-triggered NETosis. We found that before ionomycin-stimulated neutrophils release NETs, profound biochemical changes occur in a …
Here we use live-imaging microscopy and proteomic studies of the neutrophil cellular fractions to investigate the early events in ionomyc …
Ergoferon Increases IL-2 Production by Activated Lymphocytes.
Kanareikina MA, Alinkina ES, Petrova AO, Emel'yanova AG, Gorbunov EA, Tarasov SA. Kanareikina MA, et al. Bull Exp Biol Med. 2019 Apr;166(6):744-746. doi: 10.1007/s10517-019-04431-1. Epub 2019 Apr 24. Bull Exp Biol Med. 2019. PMID: 31020588
Preincubation of Jurkat cells with Ergoferon increased IL-2 secretion by these cells after stimulation with phorbol 12-myristate 13-acetate/ionomycine in comparison with the placebo group. The data prove that Ergoferon is capable of activating cell cascades involved in the …
Preincubation of Jurkat cells with Ergoferon increased IL-2 secretion by these cells after stimulation with phorbol 12-myristate 13-acetate/ …
Parthenogenetic activation of rhesus monkey oocytes and reconstructed embryos.
Mitalipov SM, Nusser KD, Wolf DP. Mitalipov SM, et al. Biol Reprod. 2001 Jul;65(1):253-9. doi: 10.1095/biolreprod65.1.253. Biol Reprod. 2001. PMID: 11420247
Following reconstruction by nuclear transfer, activation with ionomycin/6-dimethylaminopurine resulted in embryos that contained a single pronucleus and no polar bodies. ...In summary, we have identified simple yet effective methods of oocyte or cytoplast activation in the …
Following reconstruction by nuclear transfer, activation with ionomycin/6-dimethylaminopurine resulted in embryos that contained a si …
8,597 results