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Page 1
Icatibant.
[No authors listed] [No authors listed] 2023 Mar 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Mar 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 36940272 Free Books & Documents. Review.
No information is available on the excretion of icatibant into breastmilk. Because icatibant is a protein molecule with a molecular weight of 1305 Da, the amount in milk is likely to be very low. ...
No information is available on the excretion of icatibant into breastmilk. Because icatibant is a protein molecule with a mole …
Is Icatibant Safe for the Treatment of Hereditary Angioedema During Pregnancy?
Šimac DV, Štimac T, Novak S. Šimac DV, et al. Curr Allergy Asthma Rep. 2022 Oct;22(10):135-140. doi: 10.1007/s11882-022-01040-3. Epub 2022 Aug 31. Curr Allergy Asthma Rep. 2022. PMID: 36044174 Review.
This review presents current guidelines for HAE treatment with a focus on pregnancy and reviews all experience with icatibant use during pregnancy. RECENT FINDINGS: Our experience of treating a pregnant nC1-INH HAE patient with icatibant is presented, with no advers …
This review presents current guidelines for HAE treatment with a focus on pregnancy and reviews all experience with icatibant use dur …
ACE inhibitor-mediated angioedema.
Montinaro V, Cicardi M. Montinaro V, et al. Int Immunopharmacol. 2020 Jan;78:106081. doi: 10.1016/j.intimp.2019.106081. Epub 2019 Dec 10. Int Immunopharmacol. 2020. PMID: 31835086 Review.
Interventional studies with the specific bradykinin receptor antagonist icatibant have shown conflicting results; there might be a different ethnic predisposition to icatibant efficacy which has been proven in caucasian but not in black patients....
Interventional studies with the specific bradykinin receptor antagonist icatibant have shown conflicting results; there might be a di …
The Icatibant Outcome Survey: 10 years of experience with icatibant for patients with hereditary angioedema.
Maurer M, Aberer W, Caballero T, Bouillet L, Grumach AS, Botha J, Andresen I, Longhurst HJ; IOS Study Group. Maurer M, et al. Clin Exp Allergy. 2022 Sep;52(9):1048-1058. doi: 10.1111/cea.14206. Epub 2022 Aug 7. Clin Exp Allergy. 2022. PMID: 35861129 Review.
In patients with hereditary angioedema (HAE), bradykinin causes swelling episodes by activating bradykinin B(2) receptors. Icatibant, a selective bradykinin B(2) receptor antagonist, is approved for on-demand treatment of HAE attacks. The Icatibant Outcome Survey (I …
In patients with hereditary angioedema (HAE), bradykinin causes swelling episodes by activating bradykinin B(2) receptors. Icatibant, …
Efficacy of Treatment of Non-hereditary Angioedema.
van den Elzen M, Go MFCL, Knulst AC, Blankestijn MA, van Os-Medendorp H, Otten HG. van den Elzen M, et al. Clin Rev Allergy Immunol. 2018 Jun;54(3):412-431. doi: 10.1007/s12016-016-8585-0. Clin Rev Allergy Immunol. 2018. PMID: 27672078 Free PMC article. Review.
Therapies were described for angiotensin-converting enzyme inhibitor-induced AE (ACEi-AE), for idiopathic AE, and for AE with wheals. Described treatments consisted of ecallantide, icatibant, C1INH, fresh frozen plasma (FFP), tranexamic acid (TA), and omalizumab. ...In con …
Therapies were described for angiotensin-converting enzyme inhibitor-induced AE (ACEi-AE), for idiopathic AE, and for AE with wheals. Descri …
Icatibant.
Deeks ED. Deeks ED. Drugs. 2010;70(1):73-81. doi: 10.2165/11204500-000000000-00000. Drugs. 2010. PMID: 20030426
Icatibant is a selective antagonist of the bradykinin type 2 receptor. ...Across both FAST-1 and -2, the efficacy of subcutaneous icatibant 30 mg in the treatment of laryngeal episodes of hereditary angioedema was generally consistent with that seen for abdominal an …
Icatibant is a selective antagonist of the bradykinin type 2 receptor. ...Across both FAST-1 and -2, the efficacy of subcutaneous …
Icatibant for the treatment of hereditary angioedema.
Cole SW, Lundquist LM. Cole SW, et al. Ann Pharmacother. 2013 Jan;47(1):49-55. doi: 10.1345/aph.1R423. Epub 2012 Dec 18. Ann Pharmacother. 2013. PMID: 23249729 Review.

When icatibant was compared to tranexamic acid in FAST-2, the median time to clinically significant relief of the index symptom was shorter for patients receiving icatibant (p < 0.001). ...These data suggest that icatibant is a safe and effective treatment

…
When icatibant was compared to tranexamic acid in FAST-2, the median time to clinically significant relief of the index symptom was s …
New Treatments for Hereditary Angioedema.
Johnson NM, Phillips MA. Johnson NM, et al. Skin Therapy Lett. 2018 Jan;23(1):6-8. Skin Therapy Lett. 2018. PMID: 29357215 Free article. Review.
The Angiotensin-Converting-Enzyme-Induced Angioedema.
Bas M. Bas M. Immunol Allergy Clin North Am. 2017 Feb;37(1):183-200. doi: 10.1016/j.iac.2016.08.011. Immunol Allergy Clin North Am. 2017. PMID: 27886906 Review.
The bradykinin B2 receptor antagonist icatibant is effective in angiotensin-converting enzyme inhibitor-induced angioedema. ...
The bradykinin B2 receptor antagonist icatibant is effective in angiotensin-converting enzyme inhibitor-induced angioedema. ...
Icatibant use in Brazilian patients with hereditary angioedema (HAE) type 1 or 2 and HAE with normal C1-INH levels: findings from the Icatibant Outcome Survey Registry Study.
Grumach AS, Henriques MT, Bardou MLD, Pontarolli DA, Botha J, Correa M; IOS Brazil Study Group. Grumach AS, et al. An Bras Dermatol. 2022 Jul-Aug;97(4):448-457. doi: 10.1016/j.abd.2021.09.009. Epub 2022 May 30. An Bras Dermatol. 2022. PMID: 35654647 Free PMC article.
BACKGROUND: Hereditary angioedema can be caused by C1-Inhibitor (C1-INH) deficiency and/or dysfunction (HAE-1/2) or can occur in patients with normal C1-INH (HAE nC1-INH). METHODS: The Icatibant Outcome Survey (IOS; NCT01034969) registry monitors the safety and effectivene …
BACKGROUND: Hereditary angioedema can be caused by C1-Inhibitor (C1-INH) deficiency and/or dysfunction (HAE-1/2) or can occur in patients wi …
1,808 results