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136 results

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Page 1
3-Diazo-N-[(2S)-1-hy-droxy-propan-2-yl]-2-oxopropanamide.
Chen XN, Hu WH, Li XL, Xu HD. Chen XN, et al. Acta Crystallogr Sect E Struct Rep Online. 2011 May 1;67(Pt 5):o1192. doi: 10.1107/S1600536811014413. Epub 2011 Apr 22. Acta Crystallogr Sect E Struct Rep Online. 2011. PMID: 21754494 Free PMC article.
In the title compound, C(6)H(9)N(3)O(3), the 3-diazo-2-oxopropan-amide section of the mol-ecule is nearly planar, with a maximum deviation of 0.025 (1) A from the mean plane of its constituent atoms. ...Neighboring double chains in turn inter-act with each other thr …
In the title compound, C(6)H(9)N(3)O(3), the 3-diazo-2-oxopropan-amide section of the mol-ecule is nearly planar, with a maxim …
Intramolecular Carbene C-H Insertion Reactions of 2-Diazo-2-sulfamoylacetamides.
Que C, Huang P, Yang Z, Chen N, Xu J. Que C, et al. Molecules. 2019 Jul 19;24(14):2628. doi: 10.3390/molecules24142628. Molecules. 2019. PMID: 31330952 Free PMC article.
The intramolecular C-H insertions of carbenes derived from 2-diazo-2-sulfamoylacetamides were studied. 2-Diazo-2-sulfamoylacetamides were first prepared from chloroacetyl chloride and secondary amines through acylation followed by sequential treatments …
The intramolecular C-H insertions of carbenes derived from 2-diazo-2-sulfamoylacetamides were studied. 2-Diazo-2
Directing-Group-Assisted Manganese-Catalyzed Cyclopropanation of Indoles.
Dutta PK, Chauhan J, Ravva MK, Sen S. Dutta PK, et al. Org Lett. 2019 Apr 5;21(7):2025-2028. doi: 10.1021/acs.orglett.9b00150. Epub 2019 Mar 12. Org Lett. 2019. PMID: 30860389
The first manganese-catalyzed cyclopropanation of indoles is reported in moderate to excellent yield with methyl-2-diazo-2-arylacetates. This new strategy involved acetyl (COCH(3)) as the directing group and exhibited exceptional functional group tolerance. ...
The first manganese-catalyzed cyclopropanation of indoles is reported in moderate to excellent yield with methyl-2-diazo-2-ary …
C6N10O4: Thermally Stable Nitrogen-Rich Inner Bis(diazonium) Zwitterions.
Tang Y, Imler GH, Parrish DA, Shreeve JM. Tang Y, et al. Org Lett. 2019 Oct 18;21(20):8201-8204. doi: 10.1021/acs.orglett.9b02875. Epub 2019 Oct 3. Org Lett. 2019. PMID: 31580691
Two nitrogen-rich inner bis(diazonium) salts, the 4,4'-dinitro-5,5'-diazo-2,2'-bisimidazole (2) and the 4,4'-dinitro-5,5'-diazo-3,3'-bispyrazole (4) zwitterions, are described. ...
Two nitrogen-rich inner bis(diazonium) salts, the 4,4'-dinitro-5,5'-diazo-2,2'-bisimidazole (2) and the 4,4'-dinitro-5,5'-diaz …
A centrosome-localized calcium signal is essential for mammalian cell mitosis.
Helassa N, Nugues C, Rajamanoharan D, Burgoyne RD, Haynes LP. Helassa N, et al. FASEB J. 2019 Dec;33(12):14602-14610. doi: 10.1096/fj.201901662R. Epub 2019 Nov 2. FASEB J. 2019. PMID: 31682764 Free PMC article.
Local buffering of the centrosomal Ca(2+) signals, by flash photolysis of the caged Ca(2+) chelator diazo-2-acetoxymethyl ester, arrests mitosis. We also provide evidence that this Ca(2+) signal emanates from the endoplasmic reticulum. ...
Local buffering of the centrosomal Ca(2+) signals, by flash photolysis of the caged Ca(2+) chelator diazo-2-acetoxymethyl este …
Rhodium(II)-catalyzed decomposition of 3-O-(2-diazo-2-phenylacetyl)-1,2;5,6-di-O-isopropylidene-alpha-D-allofuranose: diastereoselective ether formation.
Sacui IA, Zeller M, Norris P. Sacui IA, et al. Carbohydr Res. 2008 Jul 21;343(10-11):1819-23. doi: 10.1016/j.carres.2008.04.005. Epub 2008 Apr 7. Carbohydr Res. 2008. PMID: 18439572
Standard diazo transfer to 3-O-(2-phenylacetyl)-1,2;5,6-di-O-isopropylidene-alpha-d-allofuranose (2), using p-acetamidobenzenesulfonyl azide (p-ABSA, 3) and DBU as base, provides the expected 3-O-(2-diazo-2-phenylacetyl)-1,2;5,6-di-O-isopropylidene-alpha-D-allofuran …
Standard diazo transfer to 3-O-(2-phenylacetyl)-1,2;5,6-di-O-isopropylidene-alpha-d-allofuranose (2), using p-acetamidobenzenesulfonyl azide …
Cytosolic Delivery of Proteins by Bioreversible Esterification.
Mix KA, Lomax JE, Raines RT. Mix KA, et al. J Am Chem Soc. 2017 Oct 18;139(41):14396-14398. doi: 10.1021/jacs.7b06597. Epub 2017 Oct 10. J Am Chem Soc. 2017. PMID: 28976737 Free PMC article.
Diazo compounds derived from (p-methylphenyl)glycine were screened for the ability to esterify the green fluorescent protein (GFP) in an aqueous environment. Esterification of GFP with 2-diazo-2-(p-methylphenyl)-N,N-dimethylacetamide was efficient. The esterified pr …
Diazo compounds derived from (p-methylphenyl)glycine were screened for the ability to esterify the green fluorescent protein (GFP) in an aqu …
Host-Guest Complexation by β-Cyclodextrin Enhances the Solubility of an Esterified Protein.
Cheah KM, Jun JV, Wittrup KD, Raines RT. Cheah KM, et al. Mol Pharm. 2022 Nov 7;19(11):3869-3876. doi: 10.1021/acs.molpharmaceut.2c00368. Epub 2022 Aug 29. Mol Pharm. 2022. PMID: 36036888 Free PMC article.
The carboxyl groups of a protein can be esterified by reaction with a diazo compound, 2-diazo-2-(p-methylphenyl)-N,N-dimethylacetamide. This esterification enables the entry of the protein into the cytosol of a mammalian cell, where the nascent ester groups are hydr …
The carboxyl groups of a protein can be esterified by reaction with a diazo compound, 2-diazo-2-(p-methylphenyl)-N,N-dimethyla …
Extracellular Ca²⁺ acts as a mediator of communication from neurons to glia.
Torres A, Wang F, Xu Q, Fujita T, Dobrowolski R, Willecke K, Takano T, Nedergaard M. Torres A, et al. Sci Signal. 2012 Jan 24;5(208):ra8. doi: 10.1126/scisignal.2002160. Sci Signal. 2012. PMID: 22275221 Free PMC article.
Using noninvasive photolysis of the photolabile Ca(2+) buffer diazo-2 {N-[2-[2-[2-[bis(carboxymethyl)amino]-5-(diazoacetyl)phenoxy]ethoxy]-4-methylphenyl]-N-(carboxymethyl)-, tetrapotassium salt} to reduce [Ca(2+)](e) or caged glutamate to simulate glutamatergic tra …
Using noninvasive photolysis of the photolabile Ca(2+) buffer diazo-2 {N-[2-[2-[2-[bis(carboxymethyl)amino]-5-(diazoacetyl)phe …
Unusual highly diastereoselective Rh(II)-catalyzed dimerization of 3-diazo-2-arylidenesuccinimides provides access to a new dibenzazulene scaffold.
Vepreva A, Bunev AS, Kudinov AY, Kantin G, Krasavin M, Dar'in D. Vepreva A, et al. Beilstein J Org Chem. 2022 May 11;18:533-538. doi: 10.3762/bjoc.18.55. eCollection 2022. Beilstein J Org Chem. 2022. PMID: 35615536 Free PMC article.
Formation of unusual unsymmetrical dimers or/and indenes via Rh(2)(esp)(2)-catalyzed decomposition of 3-diazo-2-arylidenesuccinimides has been investigated. The reaction proceeded under mild conditions, and its result was shown to strongly depend on the nature of th …
Formation of unusual unsymmetrical dimers or/and indenes via Rh(2)(esp)(2)-catalyzed decomposition of 3-diazo-2-arylidenesucci …
136 results