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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1826 1
1871 1
1877 1
1917 1
1918 1
1920 1
1923 1
1945 1
1946 5
1947 3
1948 3
1949 1
1952 1
1958 2
1960 1
1970 3
1975 1
1976 1
1977 1
1978 1
1979 1
1984 4
1987 2
1988 2
1989 2
1990 5
1991 4
1992 5
1993 2
1994 2
1995 3
1996 3
1997 2
1998 4
1999 5
2000 2
2001 6
2002 11
2003 11
2004 7
2005 6
2006 8
2007 9
2008 12
2009 5
2010 8
2011 13
2012 15
2013 7
2014 5
2015 3
2016 2
2017 7
2018 9
2019 13
2020 8
2021 10
2022 8
2023 13
2024 4

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261 results

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Cinchonine, a Potential Oral Small-Molecule Glucagon-Like Peptide-1 Receptor Agonist, Lowers Blood Glucose and Ameliorates Non-Alcoholic Steatohepatitis.
Xue H, Xing HJ, Wang B, Fu C, Zhang YS, Qiao X, Guo C, Zhang XL, Hu B, Zhao X, Deng LJ, Zhu XC, Zhang Y, Liu YF. Xue H, et al. Drug Des Devel Ther. 2023 May 11;17:1417-1432. doi: 10.2147/DDDT.S404055. eCollection 2023. Drug Des Devel Ther. 2023. PMID: 37197367 Free PMC article.
In addition, cinchonine reduced body weight gain and food intake in ob/ob-GAN NASH mice dose-dependently. 100 mg/kg cinchonine significantly improved liver function by reducing the ALT, ALP and LDH levels. Importantly, 100 mg/kg cinchonine ameliorated hepatic …
In addition, cinchonine reduced body weight gain and food intake in ob/ob-GAN NASH mice dose-dependently. 100 mg/kg cinchonine …
Cinchonine: A Versatile Pharmacological Agent Derived from Natural Cinchona Alkaloids.
Parveen S, Maurya N, Meena A, Luqman S. Parveen S, et al. Curr Top Med Chem. 2023 Nov 27. doi: 10.2174/0115680266270796231109171808. Online ahead of print. Curr Top Med Chem. 2023. PMID: 38031797
BACKGROUND: Cinchonine is one of the Cinchona alkaloids that is commercially extracted from the Peruvian bark of Cinchona officinalis L. ...AIM AND OBJECTIVE: This review discusses the pharmacological activity of cinchonine under different experimental conditions, i …
BACKGROUND: Cinchonine is one of the Cinchona alkaloids that is commercially extracted from the Peruvian bark of Cinchona officinalis …
Sulphate of Cinchonine.
[No authors listed] [No authors listed] Med Chir Rev. 1826 Jul;5(9):283. Med Chir Rev. 1826. PMID: 29919724 Free PMC article. Review. No abstract available.
Cinchonine-induced cell death in pancreatic cancer cells by downregulating RRP15.
Liang F, Lv Y, Qiao X, Zhang S, Shen S, Wang C, Xu G, Zou X, Wang L, Zhang B. Liang F, et al. Cell Biol Int. 2023 May;47(5):907-919. doi: 10.1002/cbin.11987. Epub 2023 Jan 22. Cell Biol Int. 2023. PMID: 36682038
Pancreatic cancer is characterized by poor prognosis and high mortality, while its treatment remains unsatisfactory. Cinchonine, a natural compound present in cinchona bark, is a potential anticancer drug. Whether cinchonine is of relevance to pancreatic cancer ther …
Pancreatic cancer is characterized by poor prognosis and high mortality, while its treatment remains unsatisfactory. Cinchonine, a na …
Cinchonine exerts anti-tumor and immunotherapy sensitizing effects in lung cancer by impairing autophagic-lysosomal degradation.
Wang H, Shi Y, Ma D, Cao M, Sun Y, Jiang X, Xu Z, Wang Y, Yang Y, Shi Y, Wang K. Wang H, et al. Biomed Pharmacother. 2023 Aug;164:114980. doi: 10.1016/j.biopha.2023.114980. Epub 2023 Jun 8. Biomed Pharmacother. 2023. PMID: 37301135 Free article.
Meanwhile, inhibiting autophagy is a promising strategy for cancer treatment. In this study, we found for the first time that Cinchonine (Cin) can act as an autophagy suppressor and exert anti-tumor effects. ...
Meanwhile, inhibiting autophagy is a promising strategy for cancer treatment. In this study, we found for the first time that Cinchonine …
Cinchonine and cinchonidine alleviate cisplatin-induced ototoxicity by regulating PI3K-AKT signaling.
Tang D, Wang X, Wu J, Li Y, Li C, Qiao X, Fan L, Chen Y, Zhu H, Zhang Z, He Y. Tang D, et al. CNS Neurosci Ther. 2024 Feb;30(2):e14403. doi: 10.1111/cns.14403. Epub 2023 Aug 14. CNS Neurosci Ther. 2024. PMID: 37577804 Free PMC article.
AIM: Cinchonine (CN) and its isomer cinchonidine (CD), two of the common cinchona alkaloids, are wildly used as antimalarial drugs. ...
AIM: Cinchonine (CN) and its isomer cinchonidine (CD), two of the common cinchona alkaloids, are wildly used as antimalarial drugs. . …
Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells.
Jin ZL, Yan W, Qu M, Ge CZ, Chen X, Zhang SF. Jin ZL, et al. Exp Ther Med. 2018 Jun;15(6):5046-5050. doi: 10.3892/etm.2018.6005. Epub 2018 Mar 29. Exp Ther Med. 2018. PMID: 29805529 Free PMC article.
Whether cinchonine is effective against human liver cancer, however, remains elusive. ...The Balb/c-nude mice experiment revealed that cinchonine suppressed HepG2 xenograft tumor growth in mice. The findings indicated that cinchonine promoted ER stress-induce …
Whether cinchonine is effective against human liver cancer, however, remains elusive. ...The Balb/c-nude mice experiment revealed tha …
Cinchonine inhibits osteoclast differentiation by regulating TAK1 and AKT, and promotes osteogenesis.
Jo YJ, Lee HI, Kim N, Hwang D, Lee J, Lee GR, Hong SE, Lee H, Kwon M, Kim NY, Kim HJ, Park JH, Kang YH, Kim HS, Lee SY, Jeong W. Jo YJ, et al. J Cell Physiol. 2021 Mar;236(3):1854-1865. doi: 10.1002/jcp.29968. Epub 2020 Jul 23. J Cell Physiol. 2021. PMID: 32700766
Cinchonine (CN) has been known to exert antimalarial, antiplatelet, and antiobesity effects. ...
Cinchonine (CN) has been known to exert antimalarial, antiplatelet, and antiobesity effects. ...
Cinchonine Prevents High-Fat-Diet-Induced Obesity through Downregulation of Adipogenesis and Adipose Inflammation.
Jung SA, Choi M, Kim S, Yu R, Park T. Jung SA, et al. PPAR Res. 2012;2012:541204. doi: 10.1155/2012/541204. Epub 2012 May 16. PPAR Res. 2012. PMID: 22675336 Free PMC article.
Cinchonine (C(19)H(22)N(2)O) is a natural compound of Cinchona bark. Although cinchonine's antiplatelet effect has been reported in the previous study, antiobesity effect of cinchonine has never been studied. ...
Cinchonine (C(19)H(22)N(2)O) is a natural compound of Cinchona bark. Although cinchonine's antiplatelet effect has been report …
Cinchonine and thiourea.
Xi Y, Shi X. Xi Y, et al. Chem Commun (Camb). 2013 Oct 7;49(77):8583-5. doi: 10.1039/c3cc40825f. Chem Commun (Camb). 2013. PMID: 23948716
261 results