Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 3
1960 10
1961 18
1962 44
1963 52
1964 60
1965 53
1966 21
1967 26
1968 21
1969 28
1970 22
1971 22
1972 21
1973 20
1974 27
1975 23
1976 29
1977 26
1978 38
1979 43
1980 44
1981 50
1982 46
1983 48
1984 54
1985 56
1986 54
1987 37
1988 32
1989 24
1990 33
1991 30
1992 28
1993 27
1994 21
1995 12
1996 25
1997 17
1998 13
1999 13
2000 22
2001 17
2002 18
2003 53
2004 24
2005 22
2006 24
2007 20
2008 31
2009 31
2010 21
2011 36
2012 49
2013 45
2014 42
2015 34
2016 38
2017 34
2018 37
2019 29
2020 39
2021 41
2022 52
2023 45
2024 12

Text availability

Article attribute

Article type

Publication date

Search Results

2,011 results

Results by year

Filters applied: . Clear all
Page 1
Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension.
Hripcsak G, Suchard MA, Shea S, Chen R, You SC, Pratt N, Madigan D, Krumholz HM, Ryan PB, Schuemie MJ. Hripcsak G, et al. JAMA Intern Med. 2020 Apr 1;180(4):542-551. doi: 10.1001/jamainternmed.2019.7454. JAMA Intern Med. 2020. PMID: 32065600 Free PMC article.
IMPORTANCE: Chlorthalidone is currently recommended as the preferred thiazide diuretic to treat hypertension, but no trials have directly compared risks and benefits. ...Chlorthalidone was associated with a significantly lower risk of diagnosed abnormal weight gain …
IMPORTANCE: Chlorthalidone is currently recommended as the preferred thiazide diuretic to treat hypertension, but no trials have dire …
Arterial Hypertension-clinical trials update 2023.
Götzinger F, Kunz M, Lauder L, Böhm M, Mahfoud F. Götzinger F, et al. Hypertens Res. 2023 Sep;46(9):2159-2167. doi: 10.1038/s41440-023-01359-y. Epub 2023 Jul 13. Hypertens Res. 2023. PMID: 37443261 Review.
The hypertension trials update summarizes the most important clincal trials on hypertension research in 2022 and early 2023. CTD - chlorthalidone, CV - cardiovascular, HCT - hydrochlorothiazide, SBP - systolic blood pressure, RDN - renal denervation *depicts systolic blood …
The hypertension trials update summarizes the most important clincal trials on hypertension research in 2022 and early 2023. CTD - chlort
Diuretics for hypertension: Hydrochlorothiazide or chlorthalidone?
Cooney D, Milfred-LaForest S, Rahman M. Cooney D, et al. Cleve Clin J Med. 2015 Aug;82(8):527-33. doi: 10.3949/ccjm.82a.14091. Cleve Clin J Med. 2015. PMID: 26270432 Free article. Review.
Hydrochlorothiazide is the most commonly used thiazide diuretic in the United States, but interest in chlorthalidone is increasing. The authors summarize the literature comparing these two agents....
Hydrochlorothiazide is the most commonly used thiazide diuretic in the United States, but interest in chlorthalidone is increasing. T …
[Which is better? Chlorthalidone or Hydrochlorothiazide].
Krämer BK, Hausberg M, Kreutz R, Wenzel U. Krämer BK, et al. MMW Fortschr Med. 2023 Apr;165(7):69-72. doi: 10.1007/s15006-023-2507-x. MMW Fortschr Med. 2023. PMID: 37016241 Review. German. No abstract available.
Chlorthalidone in advanced CKD.
Allison SJ. Allison SJ. Nat Rev Nephrol. 2022 Jan;18(1):3. doi: 10.1038/s41581-021-00514-3. Nat Rev Nephrol. 2022. PMID: 34819632 No abstract available.
Chlorthalidone: the forgotten diuretic.
Kountz DS, Goldman A, Mikhail J, Ezer M. Kountz DS, et al. Postgrad Med. 2012 Jan;124(1):60-6. doi: 10.3810/pgm.2012.01.2518. Postgrad Med. 2012. PMID: 22314115 Review.
Chlorthalidone's safety and efficacy in the management of hypertension has been demonstrated in landmark trials. ...This article reviews the comparative clinical data between chlorthalidone and hydrochlorothiazide, the pharmacologic properties that might explain som
Chlorthalidone's safety and efficacy in the management of hypertension has been demonstrated in landmark trials. ...This article revi
[All diuretics used in the treatment of hypertension are not the same].
Asil S, Atalar E. Asil S, et al. Turk Kardiyol Dern Ars. 2017 Jan;45(1):94-101. doi: 10.5543/tkda.2016.93137. Turk Kardiyol Dern Ars. 2017. PMID: 28106027 Free article. Review. Turkish.
Diuretics have been used for years to treat hypertension as both a monotherapy and in combination. Hydrochlorothiazide, indapamide, and chlorthalidone have frequently been considered in the same category as thiazide diuretics, but there is no evidence that their activities …
Diuretics have been used for years to treat hypertension as both a monotherapy and in combination. Hydrochlorothiazide, indapamide, and c
Management of hypertension in advanced kidney disease.
Georgianos PI, Agarwal R. Georgianos PI, et al. Curr Opin Nephrol Hypertens. 2022 Jul 1;31(4):374-379. doi: 10.1097/MNH.0000000000000812. Curr Opin Nephrol Hypertens. 2022. PMID: 35727171 Free PMC article. Review.
In the BLOCK-CKD trial, the investigational nonsteroidal mineralocorticoid-receptor-antagonist (MRA) KBP-5074 lowered office SBP by 7-10 mmHg relative to placebo at 84 days with a minimal risk of hyperkalaemia in patients with advanced CKD and uncontrolled hypertension. The CLICK …
In the BLOCK-CKD trial, the investigational nonsteroidal mineralocorticoid-receptor-antagonist (MRA) KBP-5074 lowered office SBP by 7-10 mmH …
Which diuretic is the preferred agent for treating essential hypertension: hydrochlorothiazide or chlorthalidone?
Germino FW. Germino FW. Curr Cardiol Rep. 2012 Dec;14(6):673-7. doi: 10.1007/s11886-012-0307-5. Curr Cardiol Rep. 2012. PMID: 22918623 Review.
Since their introduction over 50 years ago thiazide and thiazide-like diuretics have been a mainstay in the treatment of hypertension. Yet despite outcome evidence with chlorthalidone, the preponderance of usage has been with hydrochlorothiazide-either as monotherapy or in …
Since their introduction over 50 years ago thiazide and thiazide-like diuretics have been a mainstay in the treatment of hypertension. Yet d …
Hydrochlorothiazide vs. chlorthalidone as the optimal diuretic for the management of hypertension.
Tziomalos K, Athyros VG, Mikhailidis DP, Karagiannis A. Tziomalos K, et al. Curr Pharm Des. 2013;19(21):3766-72. doi: 10.2174/13816128113199990315. Curr Pharm Des. 2013. PMID: 23286433 Review.
Even though hydrochlorothiazide (HCTZ) and chlorthalidone are frequently considered interchangeable antihypertensive agents, they appear to differ both in their blood pressure lowering efficacy and in their effects on the lipid profile and on serum potassium, uric acid and …
Even though hydrochlorothiazide (HCTZ) and chlorthalidone are frequently considered interchangeable antihypertensive agents, they app …
2,011 results