Reactive oxygen species and lipoxygenases regulate the oncogenicity of NPM-ALK-positive anaplastic large cell lymphomas.
Thornber K, Colomba A, Ceccato L, Delsol G, Payrastre B, Gaits-Iacovoni F.
Thornber K, et al.
Oncogene. 2009 Jul 23;28(29):2690-6. doi: 10.1038/onc.2009.125. Epub 2009 Jun 8.
Oncogene. 2009.
PMID: 19503098
Functional studies have shown that transforming properties, namely proliferation and resistance to apoptosis, were abrogated by treatment with either NDGA or the 5-LOX inhibitor (N-(3-phenoxycinnamyl)-acetohydroxamic acid) (BW A4C). Together, th …
Functional studies have shown that transforming properties, namely proliferation and resistance to apoptosis, were abrogated by treatment wi …