Differences in metabolic behavior and liver toxicity between the optical isomers of bufenadrine hydrochloride, a substituted diphenhydramine, in the rat

Acta Pharmacol Toxicol (Copenh). 1972;31(5):369-79. doi: 10.1111/j.1600-0773.1972.tb03600.x.
No abstract available

MeSH terms

  • Animals
  • Bile / analysis
  • Biotransformation
  • Carbon Isotopes
  • Chromatography, Thin Layer
  • Ethylamines / analysis
  • Ethylamines / toxicity*
  • Ethylamines / urine
  • Feces / analysis
  • Liver / drug effects
  • Liver / metabolism*
  • Male
  • Rats
  • Respiration
  • Stereoisomerism

Substances

  • Carbon Isotopes
  • Ethylamines