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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 2
1960 3
1962 8
1963 7
1964 6
1965 4
1966 4
1967 5
1968 4
1969 4
1970 7
1971 3
1972 2
1973 6
1974 5
1975 12
1976 8
1977 4
1978 2
1979 4
1980 7
1981 11
1982 8
1983 9
1984 11
1985 10
1986 5
1987 9
1988 6
1989 4
1990 8
1991 7
1992 5
1993 2
1994 3
1995 4
1996 2
1997 5
1998 6
1999 6
2000 3
2001 3
2002 1
2003 4
2004 2
2005 3
2006 6
2007 4
2009 5
2010 4
2011 3
2012 3
2013 4
2014 3
2015 1
2016 7
2017 4
2018 4
2019 5
2020 5
2021 3
2022 4
2023 5
2024 3

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311 results

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Page 1
Triclabendazole in the treatment of human fascioliasis: a review.
Gandhi P, Schmitt EK, Chen CW, Samantray S, Venishetty VK, Hughes D. Gandhi P, et al. Trans R Soc Trop Med Hyg. 2019 Dec 1;113(12):797-804. doi: 10.1093/trstmh/trz093. Trans R Soc Trop Med Hyg. 2019. PMID: 31638149 Free PMC article. Review.
Treatment options are limited, with older effective therapies such as emetine and bithionol no longer used due to safety issues and unavailability, and most common anthelminthics having poor efficacy. ...
Treatment options are limited, with older effective therapies such as emetine and bithionol no longer used due to safety issues and u …
The potential target of bithionol against Staphylococcus aureus: design, synthesis and application of biotinylated probes Bio-A2.
Luo Y, Wen Z, Xiong Y, Chen X, Shen Z, Li P, Peng Y, Deng Q, Yu Z, Zheng J, Han S. Luo Y, et al. J Antibiot (Tokyo). 2023 Jul;76(7):406-415. doi: 10.1038/s41429-023-00618-x. Epub 2023 Apr 25. J Antibiot (Tokyo). 2023. PMID: 37185582
The bithionol binding proteins in S. aureus were identified through immunoprecipitation and LC-MS/MS with bithionol biotinylated probe. ...In conclusion, the bithionol biotinylated probe Bio-A2-1 has antibacterial and anti-biofilm activities against S. aureus …
The bithionol binding proteins in S. aureus were identified through immunoprecipitation and LC-MS/MS with bithionol biotinylat …
Infection with Fasciola hepatica.
Aksoy DY, Kerimoglu U, Oto A, Erguven S, Arslan S, Unal S, Batman F, Bayraktar Y. Aksoy DY, et al. Clin Microbiol Infect. 2005 Nov;11(11):859-61. doi: 10.1111/j.1469-0691.2005.01254.x. Clin Microbiol Infect. 2005. PMID: 16216098 Free article.
Triclabendazole is recommended as the first-line agent for the treatment of F. hepatica infection, with bithionol as an alternative....
Triclabendazole is recommended as the first-line agent for the treatment of F. hepatica infection, with bithionol as an alternative.. …
[Paragonimiasis].
Carré JC, Houmdaophet S. Carré JC, et al. Rev Pneumol Clin. 1998 Dec;54(6):359-64. Rev Pneumol Clin. 1998. PMID: 10100349 French.
A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus.
Kim W, Zou G, Hari TPA, Wilt IK, Zhu W, Galle N, Faizi HA, Hendricks GL, Tori K, Pan W, Huang X, Steele AD, Csatary EE, Dekarske MM, Rosen JL, Ribeiro NQ, Lee K, Port J, Fuchs BB, Vlahovska PM, Wuest WM, Gao H, Ausubel FM, Mylonakis E. Kim W, et al. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16529-16534. doi: 10.1073/pnas.1904700116. Epub 2019 Jul 29. Proc Natl Acad Sci U S A. 2019. PMID: 31358625 Free PMC article.
Critically, bithionol exhibits significant selectivity for bacterial compared with mammalian cell membranes. ...This work highlights the potential repurposing of bithionol as an antipersister therapeutic agent....
Critically, bithionol exhibits significant selectivity for bacterial compared with mammalian cell membranes. ...This work highlights …
Addition of ethylamines to the phenols of bithionol and synthetic retinoids does not elicit activity in gram-negative bacteria.
Cheng AV, Schrank CL, Escobar IE, Mylonakis E, Wuest WM. Cheng AV, et al. Bioorg Med Chem Lett. 2020 May 1;30(9):127099. doi: 10.1016/j.bmcl.2020.127099. Epub 2020 Mar 9. Bioorg Med Chem Lett. 2020. PMID: 32171615 Free PMC article.
Our labs have demonstrated the activity of bithionol and synthetic retinoids against methicillin-resistant Staphylococcus aureus (MRSA), as well as their membrane-acting mechanism of action. ...Thus, we find that alkylamines would not elicit broad-spectrum activity from …
Our labs have demonstrated the activity of bithionol and synthetic retinoids against methicillin-resistant Staphylococcus aureus (MRS …
In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD).
Florent RL, Becker JA, Powell MD. Florent RL, et al. Dis Aquat Organ. 2010 Sep 17;91(3):257-62. doi: 10.3354/dao02269. Dis Aquat Organ. 2010. PMID: 21133325 Free article.
The objective of the present study was to evaluate the in vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD). ...In vitro toxicity to Neoparamoeba spp. was examined using amoebae isolated from …
The objective of the present study was to evaluate the in vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba …
Paragonimus and paragonimiasis in Korea.
Choi DW. Choi DW. Kisaengchunghak Chapchi. 1990 Dec;28 Suppl:79-102. doi: 10.3347/kjp.1990.28.suppl.79. Kisaengchunghak Chapchi. 1990. PMID: 2133425 Review.
Various drugs have been introduced for the treatment of paragonimiasis, and among them, bithionol, niclofolan and praziquantel have shown high therapeutic efficacy. ...
Various drugs have been introduced for the treatment of paragonimiasis, and among them, bithionol, niclofolan and praziquantel have s …
Evaluation of bithionol as a bath treatment for amoebic gill disease caused by Neoparamoeba spp.
Florent RL, Becker JA, Powell MD. Florent RL, et al. Vet Parasitol. 2007 Mar 31;144(3-4):197-207. doi: 10.1016/j.vetpar.2006.10.018. Epub 2006 Nov 28. Vet Parasitol. 2007. PMID: 17129675 Clinical Trial.
This study examined the toxicity of bithionol to Atlantic salmon Salmo salar and rainbow trout Oncorhynchus mykiss in fresh- and seawater and the efficacy of bithionol as a 1h seawater bath treatment for amoebic gill disease (AGD). ...Efficacy was examined by bathin …
This study examined the toxicity of bithionol to Atlantic salmon Salmo salar and rainbow trout Oncorhynchus mykiss in fresh- and seaw …
Pulmonary paragonimiasis.
Mayer GJ. Mayer GJ. J Pediatr. 1979 Jul;95(1):75-6. doi: 10.1016/s0022-3476(79)80088-8. J Pediatr. 1979. PMID: 480017 No abstract available.
311 results