Improving implementation of evidence-based therapies for heart failure

Clin Cardiol. 2022 Jun;45 Suppl 1(Suppl 1):S52-S59. doi: 10.1002/clc.23845.

Abstract

Treatment options for patients with heart failure have improved rapidly over the last few decades. Data from large scale clinical trials demonstrate that medical and device therapies can improve quality of life, reduce hospitalizations for acute heart failure, and reduce mortality. However, the use of many of these therapies in routine practice is remarkably low. There are many reasons for suboptimal implementation of evidence-based therapies for heart failure, and we believe addressing the large gap between what can be accomplished in clinical trials versus routine practice is a critical and urgent public health issue. In this review, we outline reasons for this implementation gap and review recent studies attempting to address this issue. We also provide recommendations for future interventions and areas of clinical investigation to improve implementation for patients with heart failure.

Keywords: clinical trials; heart failure; implementation science; quality improvement.

Publication types

  • Review

MeSH terms

  • Heart Failure* / drug therapy
  • Heart Failure* / therapy
  • Hospitalization
  • Humans
  • Quality of Life*