COVID fog demystified

Jennifer Kao; Paul W Frankland

doi:10.1016/j.cell.2022.06.020

COVID fog demystified

Cell. 2022 Jul 7;185(14):2391-2393. doi: 10.1016/j.cell.2022.06.020. Epub 2022 Jun 15.

Authors

Jennifer Kao¹, Paul W Frankland²

Affiliations

¹ Program in Neurosciences & Mental Health, Hospital for Sick Children, 686 Bay St, Toronto, ON M5G 0A4, Canada; Department of Physiology, University of Toronto, Toronto, ON M5G 1A8, Canada.
² Program in Neurosciences & Mental Health, Hospital for Sick Children, 686 Bay St, Toronto, ON M5G 0A4, Canada; Department of Physiology, University of Toronto, Toronto, ON M5G 1A8, Canada; Department of Psychology, University of Toronto, Toronto, ON M5S 3G3, Canada; Institute of Medical Sciences, University of Toronto, Toronto, ON M5S 1A8, Canada; Child & Brain Development Program, Canadian Institute for Advanced Research, Toronto, ON M5G 1M1, Canada. Electronic address: paul.frankland@sickkids.ca.

Abstract

Acute mild respiratory SARS-CoV-2 infection can lead to a more chronic cognitive syndrome known as "COVID fog." New findings from Fernández-Castañeda et al. reveal how glial dysregulation and consequent neural circuit dysfunction may contribute to cognitive impairments in long COVID.

MeSH terms

COVID-19* / complications
Cognitive Dysfunction*
Humans
Post-Acute COVID-19 Syndrome
SARS-CoV-2