Understanding drivers of the Black:White breast cancer mortality gap: A call for more robust definitions

Cancer. 2022 Jul 15;128(14):2695-2697. doi: 10.1002/cncr.34243. Epub 2022 May 17.

Abstract

Kim et al completed a pooled analysis of 8 National Surgical Adjuvant Breast and Bowel Project trials and highlight that, when compared with White patients, Black patients with estrogen receptor–positive (ER+) breast cancer have worse distant recurrence‐free survival, especially in the setting of neoadjuvant chemotherapy when pathologic complete response is not achieved. This editorial highlights that, to comprehend the drivers of this disparity, we must have more robust definitions of ER+ breast cancer and race.

Keywords: ER+ breast cancer; NSABP; breast cancer; disparities; editorial.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Breast Neoplasms*
  • Female
  • Humans
  • Receptors, Estrogen
  • Receptors, Progesterone

Substances

  • Receptors, Estrogen
  • Receptors, Progesterone