Attrition in longitudinal studies among patients with schizophrenia and other psychoses; findings from the STRATA collaboration

Psychiatry Res. 2021 Nov:305:114211. doi: 10.1016/j.psychres.2021.114211. Epub 2021 Sep 20.

Abstract

A major problem with longitudinal studies is the bias generated due to attrition, particularly apparent amongst patients suffering from psychotic disorders. Factors associated with study-participation were investigated as part of a larger research collaboration (STRATA). Out of 479 eligible participants, only 50 (10,4%) were successfully followed up. The present study investigated whether study participation differed depending on baseline characteristics. Results indicated that individuals who did not participate were more likely to report an alcohol use disorder while those who did respond were more likely to have been in full-time education for longer and be of white ethnicity. Participation did not differ depending on diagnosis, symptoms, GAF, age of onset or depression.

Keywords: Attrition; Longitudinal studies; Psychotic disorders.

MeSH terms

  • Bias
  • Humans
  • Longitudinal Studies
  • Psychotic Disorders* / diagnosis
  • Psychotic Disorders* / epidemiology
  • Schizophrenia* / diagnosis