Severe acute respiratory syndrome coronavirus-2 in post-laryngectomy patients: case series of four patients

J Laryngol Otol. 2020 Aug;134(8):747-749. doi: 10.1017/S0022215120001310. Epub 2020 Jun 23.

Abstract

Objective: To report our experience of diagnosis, investigation and management in patients who had undergone laryngectomy secondary to previous squamous cell carcinoma, who were subsequently infected with severe acute respiratory syndrome coronavirus-2 during the coronavirus disease 2019 pandemic.

Case reports: Four post-laryngectomy patients with laboratory-proven severe acute respiratory syndrome coronavirus-2 infection were admitted to our institution from 1 March to 1 May 2020. All patients displayed symptoms of coronavirus disease 2019 and underwent investigations, including swab and serum sampling, and chest X-ray where indicated. All were managed conservatively on dedicated coronavirus disease 2019 wards and were discharged without the requirement of higher level care.

Conclusion: It is hypothesised that laryngectomy may offer a protective effect against severe or critical disease in severe acute respiratory syndrome coronavirus-2 infection. We hope sharing our experience will aid all practitioners in the management of this, often intimidating, cohort of patients.

Keywords: COVID-19; Coronavirus; Laryngectomy; Squamous Cell Carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Betacoronavirus / isolation & purification
  • COVID-19
  • Carcinoma, Squamous Cell / surgery*
  • Conservative Treatment / methods
  • Coronavirus Infections / diagnosis*
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / therapy
  • Coronavirus Infections / virology
  • Female
  • Humans
  • Laryngeal Neoplasms / pathology*
  • Laryngectomy / adverse effects*
  • Laryngectomy / methods
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Pandemics
  • Pneumonia, Viral / diagnosis*
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / therapy
  • Pneumonia, Viral / virology
  • Postoperative Complications / virology
  • SARS-CoV-2
  • Treatment Outcome