Patient and surgery factors associated with the incidence of failed and difficult intubation

Anaesthesia. 2020 Jun;75(6):756-766. doi: 10.1111/anae.14997. Epub 2020 Mar 31.

Abstract

Estimates of the rate and risk-factors for difficult airway rarely include a denominator for the number of anaesthetics. Approaches such as self-reporting and crowd-sourcing of airway incidents may help identify specific lessons from clinical episodes, but the lack of denominator data, biased reporting and under-reporting does not allow a comprehensive population-based assessment. We used an established state-wide dataset to determine the incidence of failed and difficult intubations between 2015 and 2017 in the state of Victoria in Australia, along with associated patient and surgical risk-factors. A total of 861,533 general anaesthesia episodes were analysed. Of these, 4092 patients with difficult or failed intubation were identified; incidence rates of 0.52% (2015-2016) and 0.43% (2016-2017), respectively. Difficult/failed intubations were most common in patients aged 45-75 and decreased for older age groups, with risk being lower for patients aged >85 than patients aged 35-44. The risk for failed/difficult intubation increased significantly for: patients undergoing emergency surgery (OR 1.80); obese patients (OR 2.48); increased ASA physical status; and increased Charlson Comorbidity Index. Across all age groups, procedures on the nervous system (OR 1.92) and endocrine system (OR 2.03) had the highest risk of failed/difficult intubation. The relative reduced risk for failed/difficult intubations in the elderly population is a novel finding that contrasts with previous research and may suggest a 'compression of morbidity' effect as a moderator. Administrative databases have the potential to improve understanding of peri-operative risk of rare events at a population level.

Keywords: airway management; anaesthesia; database; difficult intubation.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Anesthesia, General / statistics & numerical data
  • Child
  • Child, Preschool
  • Databases, Factual
  • Emergency Treatment / statistics & numerical data*
  • Endocrine System / surgery
  • Female
  • Health Status*
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Intubation, Intratracheal / methods*
  • Intubation, Intratracheal / statistics & numerical data*
  • Male
  • Middle Aged
  • Neurosurgical Procedures / statistics & numerical data
  • Obesity / complications*
  • Risk Factors
  • Surgical Procedures, Operative / statistics & numerical data*
  • Victoria
  • Young Adult