Mepolizumab does not alter the blood basophil count in severe asthma

Allergy. 2019 Dec;74(12):2488-2490. doi: 10.1111/all.13879. Epub 2019 Jun 28.

Authors

Adam Kelvin Alec Wright¹, Sarah Diver^{1

2}, Jamie McCarthy¹, Andrew Marvin³, Marcia Soares^{1

2}, Tracy Thornton², Michelle Bourne², Michelle Craner^{2

4}, Helen Evans², Sarah Edwards², Sarah Glover², Liesl Carr^{1

2}, Sarah Parker², Salman Siddiqui^{1

2

4}, David Cousins^{1

2}, Chris Brightling^{1

2

4}

Affiliations

¹ Department of Respiratory Sciences, University of Leicester, Leicester, UK.
² National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, University Hospitals of Leicester NHS Trust, Leicester, UK.
³ Pathology Services, University Hospitals of Leicester NHS Trust, Leicester, UK.
⁴ Respiratory Medicine, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Monoclonal, Humanized / pharmacology
Antibodies, Monoclonal, Humanized / therapeutic use*
Asthma / blood*
Asthma / diagnosis
Asthma / drug therapy*
Asthma / etiology
Basophils / drug effects*
Basophils / immunology
Humans
Leukocyte Count*
Treatment Outcome

Substances

Antibodies, Monoclonal, Humanized
mepolizumab

Grants and funding