1 From the Population Health and Optimal Health Practices Research Unit, Centre de Recherche du Centre Hospitalier Universitaire de Québec-Université Laval, and the Departments of Medicine and Anesthesiology and Critical Care Medicine, Université Laval, Quebec, QC (F.L.), and the Departments of Medicine (J.D.D., D.J.C.) and Health Research Methods, Evidence, and Impact (D.J.C.), McMaster University, and the Department of Medicine (J.D.D., D.J.C.) and the Division of Critical Care (D.J.C.), St. Joseph's Healthcare, Hamilton, ON - all in Canada.