Decision making in advanced larynx cancer: An evidenced based review

Antoine Eskander; Dukagjin M Blakaj; Peter T Dziegielewski

doi:10.1016/j.oraloncology.2018.09.019

Decision making in advanced larynx cancer: An evidenced based review

Oral Oncol. 2018 Nov:86:195-199. doi: 10.1016/j.oraloncology.2018.09.019. Epub 2018 Oct 1.

Authors

Antoine Eskander¹, Dukagjin M Blakaj², Peter T Dziegielewski³

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, Sunnybrook Health Sciences Centre and the Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.
² Department of Radiation Oncology, The Ohio State University, Columbus, OH, USA.
³ Department of Otolaryngology, University of Florida, Gainesville, FL, USA; University of Florida Health Cancer Center, Gainesville, FL, USA. Electronic address: ptd@ufl.edu.

PMID: 30409301
DOI: 10.1016/j.oraloncology.2018.09.019

Abstract

Organ preservation versus total laryngectomy for advanced laryngeal cancer continues to be hotly debated. This review presents evidence-based decision making points for these patents.

Keywords: Advanced laryngeal cancer; Chemoradiation; Functional outcomes; Laryngectomy; Organ preservation; Salvage laryngectomy.

Published by Elsevier Ltd.

Publication types

Review

MeSH terms

Chemoradiotherapy, Adjuvant / adverse effects
Chemoradiotherapy, Adjuvant / methods
Clinical Decision-Making / methods*
Disease-Free Survival
Evidence-Based Medicine / methods*
Humans
Laryngeal Neoplasms / mortality
Laryngeal Neoplasms / pathology
Laryngeal Neoplasms / therapy*
Laryngectomy / adverse effects
Laryngectomy / methods
Larynx / pathology
Larynx / radiation effects
Larynx / surgery
Neoplasm Recurrence, Local / epidemiology*
Neoplasm Recurrence, Local / prevention & control
Neoplasm Staging
Organ Sparing Treatments / adverse effects
Organ Sparing Treatments / methods
Patient Selection*
Salvage Therapy / adverse effects
Salvage Therapy / methods
Tumor Burden