Locked and Loaded: Inflammation Training Prepares Skin Epithelial Stem Cells for Trauma

Valentina Proserpio; Salvatore Oliviero; Giacomo Donati

doi:10.1016/j.stem.2017.11.013

Locked and Loaded: Inflammation Training Prepares Skin Epithelial Stem Cells for Trauma

Cell Stem Cell. 2017 Dec 7;21(6):715-717. doi: 10.1016/j.stem.2017.11.013.

Authors

Valentina Proserpio¹, Salvatore Oliviero¹, Giacomo Donati²

Affiliations

¹ Laboratory of Epigenetics, Department of Life Sciences and System Biology, University of Turin, Turin, Italy; Italian Institute for Genomic Medicine (IIGM), Turin, Italy.
² Laboratory of Stem Cell Biology, Department of Life Sciences and System Biology and Molecular Biotechnology Center, University of Turin, Turin, Italy. Electronic address: giacomo.donati@unito.it.

PMID: 29220664
DOI: 10.1016/j.stem.2017.11.013

Abstract

Memory of a trauma and how to cope with it is useful for acting rapidly in the event of a second traumatic incident. Recently, Naik et al. (2017) reported in Nature that skin epithelial stem cells have this ability by maintaining long-term chromatin features acquired during the first assault.

Publication types

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MeSH terms

Chromatin
Humans
Inflammation
Memory*
Skin*
Stem Cells

Substances

Chromatin