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Combining quantitative proteomics data processing workflows for greater sensitivity.

Colaert N, et al. Nat Methods. 2011.

Abstract

We here describe a normalization method to combine quantitative proteomics data. By merging the output of two popular quantification software packages, we obtained a 20% increase (on average) in the number of quantified human proteins without suffering from a loss of quality. Our integrative workflow is freely available through our user-friendly, open-source Rover software (http://compomics-rover.googlecode.com/).

PMID

21552256 [Indexed for MEDLINE]

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