Click to search
PubMed Mobile will be replaced by the new PubMed in early March. Click here to try the new PubMed!

Polyneuropathy caused by cobalt-chromium metallosis after total hip replacement.

Ikeda T, et al. Muscle Nerve. 2010.

Abstract

Although metal intoxication after arthroplasty causes various symptoms, polyneuropathy has never been the focus of clinical investigation. We report the case of a 56-year-old woman with metal neuropathy. She had metallosis after hip arthroplasty with a cobalt-chromium alloy prosthesis. She developed progressive sensory disturbance, hearing loss, and hypothyroidism. Sural nerve biopsy indicated axonopathy. After exchange arthroplasty, blood levels of cobalt and chromium decreased, and her symptoms improved. Cobalt or chromium can cause axonopathy.

PMID

20544916 [Indexed for MEDLINE]

Full text

Comment in