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NIH Director's Blog TODAY

The Amazing Brain: Deep Brain Stimulation for OCD

The winners of the “Show Us Your Brain!” Photo and Video contest are chosen each year based on their eye-catching ability to capture the creative spirit of the Brain Research Through Innovative Technologies® (BRAIN) Initiative. This year’s first-place video certainly fits the bill while highlighting encouraging efforts to help people with the most severe and hard-to-treat form of obsessive compulsive disorder (OCD), a psychiatric illness marked by recurrent unwanted or distressing thoughts and repetitive behaviors.

NLM Musings YESTERDAY

The Public Libraries are Opening! The Public Libraries are Opening!

Of all the wonderful signs and sounds heralding a change in the response to the COVID-19 pandemic, none is more welcome than the news that public libraries are reopening. If you, like me, remember spending hot summer afternoons in the cool, air-conditioned library, this mid-summer news may bring a smile to your face. For me, … Continue reading "The Public Libraries are Opening! The Public Libraries are Opening!"

NIH Director's Blog AUG. 3, 2021

The Amazing Brain: Toward a Wiring Diagram of Connectivity

It’s summertime and, thanks to the gift of COVID-19 vaccines, many folks are getting the chance to take a break. So, I think it’s also time that my blog readers finally get a break from what’s been nearly 18 months of non-stop coverage of COVID-19 research. And I can’t think of a more enjoyable way to do that than by taking a look at just a few of the many spectacular images and insights that researchers have derived about the amazing brain.

Research news

NIH News Releases YESTERDAY

Full-dose blood thinners reduce the need for organ support in moderately ill COVID-19 patients, but not in critically ill patients

The final analysis of trial data included 1,098 critically ill and 2,219 moderately ill hospitalized patients who received either a low or full dose of heparin for up to 14 days after enrollment.

The New York Times YESTERDAY

Heart problems following vaccination in the U.S. are uncommon and short-lived, researchers reported.

These heart problems are far more common among patients who develop Covid-19, outside experts noted.

More news COVID-19 news

NCBI databases

NCBI Virus

The most up-to-date set of SARS‑CoV‑2 nucleotide and protein sequences

LitCovid

A curated literature hub for the latest scientific information on COVID-19

BLAST

Use our new Betacoronavirus database for SARS‑CoV‑2 genome sequence analysis

Literature

The World's largest repository of medical and scientific abstracts, full-text articles, books and reports

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

HomoloGene

Homologous genes sets for selected organisms

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Family Models

Models representing homologous proteins with a common function

Structure

Experimentally-determined biomolecular structures

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

BLAST

A tool to find regions of similarity between biological sequences

blastn

Search nucleotide sequence databases

blastp

Search protein seqeuence databases

blastx

Search protein databases using a translated nucleotide query

tblastn

Search translated nucleotide databases using a protein query

Primer-BLAST

Find primers specific to your PCR template

Clinical

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinicalTrials.gov

Privately and publicly funded clinical studies conducted around the world

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

PubChem

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioAssays

Bioactivity screening studies

Compounds

Chemical information with structures, information and links

Pathways

Molecular pathways with links to genes, proteins and chemicals

Substances

Deposited substance and chemical information