Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

COVID-19 resources

COVID-19 treatment

Coronavirus Disease 2019 (COVID-19) Treatment Guidelines (National Institutes of Health)

BLAST

Use our new Betacoronavirus database for SARS‑CoV‑2 genome sequence analysis

NCBI Virus

The most up-to-date set of SARS‑CoV‑2 nucleotide and protein sequences

Literature

PubMed

PubMed® comprises more than 34 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites.

Literature databases

Bookshelf

Books and reports

MeSH

Ontology used for PubMed indexing

NLM Catalog

Books, journals and more in the NLM Collections

PubMed

Scientific and medical abstracts/citations

PubMed Central

Full-text journal articles

Data

Genes

Gene sequences and annotations used as references for the study of orthologs structure, expression, and evolution

Gene

Collected information about gene loci

GEO DataSets

Functional genomics studies

GEO Profiles

Gene expression and molecular abundance profiles

HomoloGene

Homologous genes sets for selected organisms

PopSet

Sequence sets from phylogenetic and population studies

Proteins

Protein sequences, 3-D structures, and tools for the study of functional protein domains and active sites

Conserved Domains

Conserved protein domains

Identical Protein Groups

Protein sequences grouped by identity

Protein

Protein sequences

Protein Family Models

Models representing homologous proteins with a common function

Structure

Experimentally-determined biomolecular structures

BLAST

A tool to find regions of similarity between biological sequences

blastn

Search nucleotide sequence databases

blastp

Search protein sequence databases

blastx

Search protein databases using a translated nucleotide query

tblastn

Search translated nucleotide databases using a protein query

Primer-BLAST

Find primers specific to your PCR template

Genomes

Genome sequence assemblies, large-scale functional genomics data, and source biological samples

Assembly

Genome assembly information

BioCollections

Museum, herbaria, and other biorepository collections

BioProject

Biological projects providing data to NCBI

BioSample

Descriptions of biological source materials

Genome

Genome sequencing projects by organism

Nucleotide

DNA and RNA sequences

SRA

High-throughput sequence reads

Taxonomy

Taxonomic classification and nomenclature

Clinical

Heritable DNA variations, associations with human pathologies, and clinical diagnostics and treatments

ClinicalTrials.gov

Privately and publicly funded clinical studies conducted around the world

ClinVar

Human variations of clinical significance

dbGaP

Genotype/phenotype interaction studies

dbSNP

Short genetic variations

dbVar

Genome structural variation studies

GTR

Genetic testing registry

MedGen

Medical genetics literature and links

OMIM

Online mendelian inheritance in man

PubChem

Repository of chemical information, molecular pathways, and tools for bioactivity screening

BioAssays

Bioactivity screening studies

Compounds

Chemical information with structures, information and links

Pathways

Molecular pathways with links to genes, proteins and chemicals

Substances

Deposited substance and chemical information

News

Research news

The Washington Post DECEMBER 5, 2022

Ancient human relative used fire, surprising discoveries suggest

Charcoal and burned bones offer intriguing — if controversial — clues that the species Homo naledi made hearths to light its way and cook in dark caves.

NPR News DECEMBER 4, 2022

Death metal singers have a vocal counterpart ... in bats

Bats and death metal singers have more in common than a love of the dark. A new study has found that some of bats' lower frequency calls appear to use a technique similar to death metal growling.

More news

Recent blog posts

NLM Musings TODAY

Anticipating a Future We Never Anticipated

During the summer of 2017, my first summer as Director of the National Library of Medicine, Joyce Backus—our then-NLM Associate Director for Library Operations (ADLO)—approached me with a wild idea: “How about we engage an architectural firm to guide renovations of our library space?” Joyce was a forward-thinking ADLO and had already done much to … Continue reading "Anticipating a Future We Never Anticipated"

NIH Director's Blog YESTERDAY

Experimental mRNA Vaccine May Protect Against All 20 Influenza Virus Subtypes

Flu season is now upon us, and protecting yourself and loved ones is still as easy as heading to the nearest pharmacy for your annual flu shot. These vaccines are formulated each year to protect against up to four circulating strains of influenza virus, and they generally do a good job of this. What they can’t do is prevent future outbreaks of more novel flu viruses that occasionally spill over from other species into humans, thereby avoiding a future influenza pandemic.

NCBI Insights DEC. 1, 2022

Announcing the NCBI SARS-CoV-2 Variant Calling Pipeline and Related Data Products

Still waiting for an analysis pipeline that can uniformly process raw sequence data produced by a variety of sequencing platforms? Your wait is over! Announcing the SARS-CoV-2 Variant Calling Pipeline, which is now operational and optimized to provide support for multiple sequencing platforms including, Illumina, Oxford Nanopore, and PacBio. This new pipeline can make allele … Continue reading Announcing the NCBI SARS-CoV-2 Variant Calling Pipeline and Related Data Products