Caenorhabditis elegans predicted gene dom-6, encoding cyclin-dependent kinase regulatory subunit, downstream Of Mes-6, in same operon.
SUMMARY back to top
[Wormbase] A homolog of Cks/Suc1, a highly conserved member of the eukaryotic cell cycle machinery that affects both meiosis and mitosis and has a role in the inactivation of the M-phase promoting factor (MPF) during early embryogenesis.
Map on chromosome IV, links to other databases and other names
Map: This gene dom-6 maps on chomosome IV at position +4.46 (interpolated).
Links to: WormBase, RNAiDB.
as Other names: The gene is also known cks-1, in Wormgenes/AceView by its positional name 4J279, in Wormbase by its cosmid.number name C09G4.3.
Closest AceView homologs in other species ?
The closest human genes, according to BlastP, are the AceView genes CKS1BP3, CKS1B, LOC652904, CKS1BP2, CKS1A, CKS2.
The closest mouse gene, according to BlastP, is the AceView gene Cks2 (e=4 10-23).
The closest A.thaliana genes, according to BlastP, are the AceView genes CKS2, CKS1\/CKS1AT
          Complete gene on genome diagram: back to top
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This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones.
Compact gene diagram back to top
Gene dom-6 5' 3' encoded on plus strand of chromosome IV from 8,513,903 to 8,514,712 0bp 0 Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
Sequences: click on the numbers to get the DNA back to top
Summaries of AceView transcripts and proteins back to top
Predicted protein properties back to top
Gene neighbors and Navigator on chromosome IV back to top
C I P sru-7 C mesp-1 D P mes-6C D C I R P dom-6 C I P 4J301 C R 4J267 C R 4J260 D C R P acdh-13 D C R P 4J268 5kb 0 4J253, 7 accessions sru-7, 8 accessions mesp-1, 102 accessions mes-6C, 66 accessions 10 variants dom-6, 0 accession 4J301, 57 accessions, 12 variants 4J267, 25 accessions, 3 variants 4J260, 34 accessions acdh-13, 33 accessions 5 variants 4J268, 45 accessions, 4 variants ZOOM OUT                 D:disease, C:conserved, I:interactions, R:regulation, P:publications         Read more...
Bibliography back to top
Please see these 3 articles in PubMed.
In addition we found 4 papers for which we do not have a PubMed identifier
? Gene Summary Gene on genome mRNA Expression Tissue Function, regulation, related genes CI

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function, regulation, related genes ' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To see the mRNA diagram, sequence and annotation, click the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

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