Caenorhabditis elegans gene aex-5, aboc, EXpulsion defective, encoding kex-2 Proprotein Convertase.
SUMMARY back to top
[Wormbase] an ortholog of calcium-dependent serine endoproteinases, the kex2/subtilisin-like proprotein convertase that affects defecation cycle and anterior body contractions; and is expressed in all muscle cells except pharyngeal muscles.
Map on chromosome I, links to other databases and other names
Map: This gene aex-5 maps on chomosome I at position +27.27 (interpolated).
Links to: WormBase, RNAiDB.
as Other names: The gene is also known kpc-3, kpc-5, in Wormgenes/AceView by its positional name 1P448, in Wormbase by its cosmid.number name F32A7.6.
          Complete gene on genome diagram: back to top
Please choose between the zoomable GIF version., and the HTML5/SVG version.
This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones.
Compact gene diagram back to top
Gene aex-5 5' 3' encoded on minus strand of chromosome I from 14,855,887 to 14,850,043 0bp 0 Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
Sequences: click on the numbers to get the DNA back to top
Summaries of AceView transcripts and proteins back to top
Predicted protein properties back to top
Gene neighbors and Navigator on chromosome I back to top
C R 1P433 C R 1P441 D C R P str-245 C R 1P465 C unc-122 D C I P 1P424 D C I R P eva-1 D C R P aex-5 D C I R P unc-54 5kb 0 srw-93, 7 accessions, 2 variants 1P433, 45 accessions 1P441, 83 accessions, 9 variants str-245, 9 accessions 2 variants 1P465, 7 accessions, 2 variants unc-122, 11 accessions 2 variants 1P424, 1 accession eva-1, 41 accessions, 3 variants aex-5, 0 accession unc-54, 327 accessions 8 variants frm-1, 89 accessions, 13 variants ZOOM OUT                 D:disease, C:conserved, I:interactions, R:regulation, P:publications         Read more...
Bibliography back to top
Please see these 3 articles in PubMed.
In addition we found 6 papers for which we do not have a PubMed identifier
? Gene Summary Gene on genome mRNA Expression Tissue Function, regulation, related genes DC

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function, regulation, related genes ' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To see the mRNA diagram, sequence and annotation, click the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

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