Homo sapiens complex locus DHRS4L1, encoding dehydrogenase/reductase (SDR family) member 4 like 1.
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SUMMARY back to top
RefSeq annotates one representative transcript (NM included in AceView variant.c), but Homo sapiens cDNA sequences in GenBank, dbEST, Trace and SRA, filtered against clone rearrangements, coaligned on the genome and clustered in a minimal non-redundant way by the manually supervised AceView program, support at least 12 spliced variants.

AceView synopsis, each blue text links to tables and details
Note that this locus is complex: it appears to produce several proteins with no sequence overlap.
Expression: According to AceView, this gene is well expressed, 0.4 times the average gene in this release. The sequence of this gene is defined by 49 GenBank accessions from 46 cDNA clones, some from hypothalamus (seen 4 times), pooled, cerebellum, kidney, placenta,testis, lung, colon, liver, heart, thyroid, bladder,uterus, PCR rescued clones (2), prostate (2), alzheimer cortex (once), bone marrow (once), brain (once), esophageal, tumor tissue (once) and 13 other tissues.
Alternative mRNA variants and regulation: The gene contains 21 distinct introns (20 gt-ag, 1 other). Transcription produces 13 different mRNAs, 12 alternatively spliced variants and 1 unspliced form. There are 2 probable alternative promotors and 3 non overlapping alternative last exons (see the diagram). The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of 11 cassette exons, overlapping exons with different boundaries.
Function: There are 2 articles specifically referring to this gene in PubMed. Functionally, the gene has been proposed to participate in a process (oxidation reduction). Proteins are expected to have molecular functions (binding, oxidoreductase activity) and to localize in mitochondrion.
Protein coding potential: 7 spliced mRNAs putatively encode good proteins, altogether 7 different isoforms (6 complete, 1 partial), some containing short chain dehydrogenase domain [Pfam], a peroxisomal domain [Psort2]. The remaining 6 mRNA variants (5 spliced, 1 unspliced; 2 partial) appear not to encode good proteins.

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12.
Map on chromosome 14, links to other databases and other names
Map: This gene DHRS4L1 maps on chromosome 14, at 14q11.2 according to Entrez Gene. In AceView, it covers 44.37 kb, from 24476213 to 24520586 (NCBI 37, August 2010), on the direct strand.
Links to: the SNP view, gene overviews from Entrez Gene 728635, GeneCards, expression data from ECgene, UniGene, molecular and other annotations from UCSC. The previous AceView annotation is here.
Other names: The gene is also known as DHRS4L1 or SDR25C4, LOC728635. It has been described as putative dehydrogenase/reductase SDR family member 4-like 2, short chain dehydrogenase/reductase family 25C, member 4.
Closest AceView homologs in other species ?
The closest mouse gene, according to BlastP, is the AceView gene Dhrs4 (e=10-16).
The closest C.elegans gene, according to BlastP, is the AceView/WormGene dhs-13 (e=7 10-05), which may contain interesting functional annotation.
The closest A.thaliana gene, according to BlastP, is the AceView gene AT4G05530 (e=4 10-06), which may contain interesting functional annotation
RNA_seq discoveries back to top
Expression/conservation in primates tissues evaluated by cross-mapping to human. back to top
DHRS4L1 Gene expression in 15 primates, 16 tissues, from the NHPRTR project in sFPKM BAB SkeletalMuscle WholeBlood CHP Kidney Liver Lung Spleen CMC CMM Cerebellum HUM Brain Colon Heart LymphNode Ovary Testis JMI BoneMarrow MLM OWL PTM RMC RMI Pituitary SQM Thymus MST SMY RTL 0.96 1.35 10.8 11.6 0.34 0.27 0.51 0.39 0.72 1.02 0.78 2.35 0.96 1.18 4.10 0.55 0.96 1.18 1.45 2.90 1.45 2.19 0.72 0.59 1.02 0.45 0.63 0.59 49.7 57.1 53.2 1.10 0.55 0.45 4.10 4.71 17.6 10.1 1.55 1.26 0.51 0.39 0.27 4.10 0.26 3.82 0.42 0.16 0.21 0.63 0.45 0.89 1.66 1.91 0.89 0.27 0.55 0.26 0.63 0.48 0.89 1.02 28.5 4.71 1.66 1.78 0.96 1.26 5.04 2.70 0.51 0.68 23.2 1.78 0.78 0.83 0.59 0.68 4.10 3.10 1.35 0.78 0.26 6.65 3.82 40.3 18.8 0.78 1.26 1.55 0.72 1.26 3.33 0.22 0.72 0.29 0.26 0.34 0.45 0.21 0.39 0.24 1.66 40.3 1.91 0.51 23.2 6.65 1.78 0.96 6.21 0.63 2.35 9.41 0.89 2.35 11.6 3.82 0.51 0.83 3.33 1.18 0.39 1.45 1.10 0.45 0.68 0.89 0.83 5.79 32.8 21.6 1.55 2.35 1.55 1.10 2.90 0.68 0.83 0.48 1.45 0.42 0.55 Expression quantiles None Weak 1 2 3 4 5 6 7 8 10 20 This gene All genes log2 distributions RNA-seq gene expression profile across 16 selected tissues from the Non-Human Primates Reference Transcriptome Resource (link to NHPRTR project).
- Primates: Apes (HUM: Human (Illumina BodyMap 2), CHP: Chimpanzee), Old World monkeys (PTM: Pig-Tailed Macaque, JMI Japanese Macaque, RMI Rhesus Macaque Indian, RMC Rhesus Macaque Chinese, CMM Cynomolgus Macaque Mauritian, CMC Cynomolgus Macaque Chinese, BAB Olive Baboon, SMY Sooty Mangabey); New World monkeys (MST common Marmoset, SQM Squirrel Monkey, OWL Owl Monkey); and Lemurs (MLM Mouse Lemur, RTL Ring-Tailed Lemur).
- The level for significantly expressed genes is color coded in 8 equal sized bins (light to dark green). Light gray is for weak not-accurately measured expression (2 to 8 reads above intergenic background); dark gray for no expression or no sequence conservation (0 read in gene). The plot to the right shows the distribution of measured expression values in all tissues for all genes (blue) and for this gene (green), in Magic index = log2(1000 sFPKM).
You may also examine the strand-specific genome coverage plots on the experimental AceView/Magic hub at UCSC, by tissue or by species. Tracks may be slow to load; please reload if some tracks come up yellow-greenish, and thanks to UCSC for the great work!.
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          Complete gene on genome diagram: back to top
Please choose between the zoomable GIF version., and the HTML5/SVG version.
This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones.
Compact gene diagram back to top
Gene DHRS4L1 5' 3' encoded on plus strand of chromosome 14 from 24,476,213 to 24,520,586 1 a i-u 116 8 938 870 b 88 1 1 1 1 23 938 870 c [NM] 88 d 52 938 870 e 83 938 870 f 4244 g 63 503 938 870 h 99 38 64 938 870 j 99 503 938 870 k 102 503 938 870 l 99 99 870 m 1 2kb 0 452 bp exon 26611 bp [gt-ag] intron 1 GenBank accession 125 bp exon 125 bp exon Sequence gap 3573 bp 551 bp exon 1 accession from brain capped 5' end, 1 accession 551 bp exon 919 bp exon 919 bp exon 1 accession 919 bp exon 402 bp exon 30281 bp [gt-ag] intron 1 GenBank accession 115 RNA-seq supporting reads 20 UHR pooled cells 19 Brain 2 Blood 74 Neuroblastoma 265 bp exon 265 bp exon 10669 bp [gt-ag] intron 1 GenBank accession 7 RNA-seq supporting reads 2 Brain 5 Neuroblastoma 135 bp exon 473 bp [gt-ag] intron 24 GenBank accessions 914 RNA-seq supporting reads 106 UHR pooled cells 60 Brain 43 Blood 701 Neuroblastoma 4 Other (also 2906 Primates bodymap) 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 524 bp exon 12 accessions, some from prostate (seen 2 times) germinal center B cell (once) heart (once), lung (once) lung tumor (once) Validated 3' end, 4 accessions 524 bp exon 128 bp exon 1114 bp [gt-ag] intron 2 GenBank accessions 86 RNA-seq supporting reads 28 UHR pooled cells 11 Brain 47 Neuroblastoma 178 bp exon 4767 bp [gt-ag] intron only supported by one RefSeq model 54 bp exon 1069 bp [gt-ag] intron only supported by one RefSeq model 53 bp exon 53 bp exon 4292 bp [cc-ag] fuzzy intron only supported by one RefSeq model 71 bp exon 99 bp [gt-ag] intron only supported by one RefSeq model 52 bp exon 299 bp [gt-ag] intron 1 GenBank accession 22 RNA-seq supporting reads 22 Neuroblastoma (also 59 Primates bodymap) 135 bp exon 473 bp [gt-ag] intron 24 GenBank accessions 914 RNA-seq supporting reads 106 UHR pooled cells 60 Brain 43 Blood 701 Neuroblastoma 4 Other (also 2906 Primates bodymap) 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 518 bp exon 1 accession, NM_001082488.1 518 bp exon 152 bp exon 152 bp exon 1114 bp [gt-ag] intron 2 GenBank accessions 86 RNA-seq supporting reads 28 UHR pooled cells 11 Brain 47 Neuroblastoma 393 bp exon 3 accessions, some from head neck (seen once) 393 bp exon 190 bp exon 12048 bp [gt-ag] intron 2 GenBank accessions 50 RNA-seq supporting reads 5 UHR pooled cells 10 Brain 35 Neuroblastoma 135 bp exon 135 bp exon 473 bp [gt-ag] intron 24 GenBank accessions 914 RNA-seq supporting reads 106 UHR pooled cells 60 Brain 43 Blood 701 Neuroblastoma 4 Other (also 2906 Primates bodymap) 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 522 bp exon 2 accessions, some from bone marrow (seen once) 522 bp exon 231 bp exon 41215 bp [gt-ag] intron 1 GenBank accession 82 RNA-seq supporting reads 5 UHR pooled cells 12 Brain 1 Blood 64 Neuroblastoma 135 bp exon 135 bp exon 473 bp [gt-ag] intron 24 GenBank accessions 914 RNA-seq supporting reads 106 UHR pooled cells 60 Brain 43 Blood 701 Neuroblastoma 4 Other (also 2906 Primates bodymap) 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 48 bp exon 1 accession 48 bp exon 458 bp exon 458 bp exon 458 bp exon 17830 bp [gt-ag] intron 9 GenBank accessions 4235 RNA-seq supporting reads 230 UHR pooled cells 547 Brain 239 Blood 3191 Neuroblastoma 28 Other (also 37 Primates bodymap) 9 accessions, some from hypothalamus (seen 4 times) alzheimer cortex (once) esophageal, tumor tissue (once) human skeletal muscle (once) placenta cot 25-normalized (once) capped 5' end, 2 accessions 662 bp exon 217 bp exon 1778 bp [gt-ag] intron 1 GenBank accession 62 RNA-seq supporting reads 11 UHR pooled cells 3 Brain 1 Blood 47 Neuroblastoma 178 bp exon 10092 bp [gt-ag] intron 11 GenBank accessions 492 RNA-seq supporting reads 61 UHR pooled cells 60 Brain 10 Blood 359 Neuroblastoma 2 Other 135 bp exon 135 bp exon 473 bp [gt-ag] intron 24 GenBank accessions 914 RNA-seq supporting reads 106 UHR pooled cells 60 Brain 43 Blood 701 Neuroblastoma 4 Other (also 2906 Primates bodymap) 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 522 bp exon 1 accession 522 bp exon 187 bp exon 1695 bp [gt-ag] intron 15 GenBank accessions 84 RNA-seq supporting reads 3 UHR pooled cells 3 Brain 7 Blood 71 Neuroblastoma 261 bp exon 9571 bp [gt-ag] intron 5 GenBank accessions 33 RNA-seq supporting reads 5 UHR pooled cells 28 Neuroblastoma 96 bp exon 425 bp [gt-ag] intron 5 GenBank accessions 59 RNA-seq supporting reads 5 UHR pooled cells 2 Brain 52 Neuroblastoma (also 2 Primates bodymap) 135 bp exon 135 bp exon 473 bp [gt-ag] intron 24 GenBank accessions 914 RNA-seq supporting reads 106 UHR pooled cells 60 Brain 43 Blood 701 Neuroblastoma 4 Other (also 2906 Primates bodymap) 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 175 bp exon 5 accessions, some from pooled cerebellum, kidney, placenta testis, lung, colon, liver heart, thyroid, bladder uterus, PCR rescued clones (seen once) 175 bp exon 192 bp exon 1695 bp [gt-ag] intron 15 GenBank accessions 84 RNA-seq supporting reads 3 UHR pooled cells 3 Brain 7 Blood 71 Neuroblastoma 261 bp exon 10092 bp [gt-ag] intron 11 GenBank accessions 492 RNA-seq supporting reads 61 UHR pooled cells 60 Brain 10 Blood 359 Neuroblastoma 2 Other 135 bp exon 135 bp exon 473 bp [gt-ag] intron 24 GenBank accessions 914 RNA-seq supporting reads 106 UHR pooled cells 60 Brain 43 Blood 701 Neuroblastoma 4 Other (also 2906 Primates bodymap) 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 175 bp exon 9 accessions, some from pooled cerebellum, kidney, placenta testis, lung, colon, liver heart, thyroid, bladder uterus, PCR rescued clones (seen once) 175 bp exon 231 bp exon 30945 bp [gt-ag] intron 1 GenBank accession 101 RNA-seq supporting reads 10 UHR pooled cells 18 Brain 1 Blood 72 Neuroblastoma 178 bp exon 10092 bp [gt-ag] intron 11 GenBank accessions 492 RNA-seq supporting reads 61 UHR pooled cells 60 Brain 10 Blood 359 Neuroblastoma 2 Other 135 bp exon 135 bp exon 473 bp [gt-ag] intron 24 GenBank accessions 914 RNA-seq supporting reads 106 UHR pooled cells 60 Brain 43 Blood 701 Neuroblastoma 4 Other (also 2906 Primates bodymap) 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 48 bp exon 1 accession 48 bp exon 128 bp exon 1695 bp [gt-ag] intron 15 GenBank accessions 84 RNA-seq supporting reads 3 UHR pooled cells 3 Brain 7 Blood 71 Neuroblastoma 261 bp exon 261 bp exon 10700 bp [gt-ag] intron 1 GenBank accession 98 RNA-seq supporting reads 31 UHR pooled cells 12 Brain 55 Neuroblastoma 56 bp exon 1513 bp [gt-ag] intron 24 GenBank accessions 846 RNA-seq supporting reads 85 UHR pooled cells 77 Brain 46 Blood 638 Neuroblastoma (also 753 Primates bodymap) 1 accession 48 bp exon Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
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Sequences: click on the numbers to get the DNA back to top
mRNA variant mRNA matching the genome Best predicted protein 5' UTR 3' UTR Upstream sequence Transcription
unit
pre-mRNA
Downstream sequence
aAug10 1795 bp 350 aa 464 bp 278 bp 2kb including Promoter 31312 bp 1kb
bAug10 1382 bp 150 aa 520 bp 409 bp 2kb possibly including promoter 44318 bp 1kb
cAug10 1245 bp 144 aa 407 bp 403 bp 2kb possibly including promoter 14871 bp 1kb
dAug10 545 bp 142 aa 24 bp 92 bp 2kb possibly including promoter 1659 bp 1kb
eAug10 903 bp 57 aa 322 bp 407 bp 2kb probably including promoter 14937 bp 1kb
fAug10 470 bp 35 aa 363 bp 2kb possibly including promoter 43671 bp 1kb
gAug10 1120 bp 141 aa 29 bp 665 bp 2kb including Promoter 18950 bp 1kb
hAug10 1108 bp 57 aa 527 bp 407 bp 2kb 14964 bp 1kb
iAug10-unspliced 919 bp 23 aa 716 bp 131 bp 2kb 919 bp 1kb
jAug10 910 bp 57 aa 676 bp 60 bp 2kb probably including promoter 14587 bp 1kb
kAug10 819 bp 57 aa 585 bp 60 bp 2kb probably including promoter 14592 bp 1kb
lAug10 648 bp 35 aa 541 bp 2kb 43671 bp 1kb
mAug10 493 bp 77 aa 259 bp 2kb 14401 bp 1kb

Gene neighbors and Navigator on chromosome 14q11.2 back to top
R C R DHRS2 D C R P R DHRS4 C R P C DHRS4L2 C R P C DHRS4L1 C R P C LRRC16B C R P CPNE6 D C I R P PCK2 D C R P DCAF11andFITM1 C I R P PSME1 D C I R P R RNF31andIRF9 D C I R P REC8 D C I R P R R TSSK4 C I R P C GMPR2 C R P R C14orf21andLTB4R2 D C R P LTB4R D C I R P NFATC4 D C I R P NYNRIN C I R P KHNYN C R P C I R P R D C R P C14orf165 R C14orf167 D C I R P NRL C I R P FAM158A C I R P PSME2 D C I R P NEDD8_ C C R D C I R P TINF2 D C I R P TGM1 C I R P RABGGTA C I R P DHRS1 C I R P CIDEB D C I R P RIPK3andADCY4 C C I R P CBLN3 C R P SDR39U1 100kb 0 THTPA, 290 accessions 15 variants sparpy, 58 accessions 9 variants spawpy, 18 accessions 4 variants DHRS2, 335 accessions 15 variants storcharbu, 7 accessions 6 variants DHRS4, 255 accessions 18 variants speypy, 1 accession DHRS4L2, 246 accessions 26 variants buchawbu, 2 accessions DHRS4L1, 47 accessions 13 variants leyslo, 2 accessions LRRC16B, 45 accessions 8 variants CPNE6, 307 accessions 18 variants PCK2, 335 accessions, 21 variants DCAF11andFITM1, 765 accessions 52 variants PSME1, 483 accessions 13 variants starpy, 7 accessions RNF31andIRF9, 591 accessions 35 variants REC8, 572 accessions, 17 variants waheru, 1 accession ferswey, 7 accessions TSSK4, 25 accessions, 6 variants gaswey, 1 accession GMPR2, 533 accessions 26 variants swupy, 24 accessions, 4 variants C14orf21andLTB4R2, 256 accessions 7 variants LTB4R, 115 accessions 6 variants NFATC4, 586 accessions 31 variants NYNRIN, 105 accessions 4 variants KHNYN, 423 accessions 11 variants bapu, 36 accessions, 12 variants steeswer, 2 accessions sworslu, 1 accession riromi, 2 accessions, 2 variants sterswer, 1 accession seymarby, 1 accession reromi, 1 accession stercharbu, 1 accession tormarby, 1 accession steycharbu, 1 accession swuswer, 1 accession swoswer, 1 accession chomarby, 1 accession swawcharbu, 1 accession cheemarby, 1 accession swarswer, 9 accessions swercharbu, 1 accession swawswer, 2 accessions geyvar, 3 accessions bachawbu, 2 accessions rutaru, 1 accession kuslo, 1 accession muslo, 2 accessions gorvar, 1 accession bawswey, 1 accession beeswey, 1 accession berswey, 1 accession neyskoy, 9 accessions borswey, 1 accession peyslo, 1 accession daswey, 1 accession tarsoybo, 1 accession rarslo, 1 accession boychawbu, 1 accession dachawbu, 1 accession fyswey, 1 accession merzor, 11 accessions skawmarby, 1 accession feyswey, 2 accessions deechawbu, 1 accession smumarby, 2 accessions garswey, 2 accessions gawswey, 1 accession gerswey, 1 accession geyswey, 2 accessions sparmarby, 1 accession goyswey, 2 accessions jaswey, 1 accession fachawbu, 1 accession juswey, 1 accession spawmarby, 1 accession joswey, 4 accessions fychawbu, 1 accession jarswey, 1 accession jawswey, 1 accession fochawbu, 1 accession sweymarby, 1 accession fawchawbu, 2 accessions kyswey, 3 accessions ferchawbu, 1 accession swoypy, 21 accessions fumawby, 1 accession karswey, 2 accessions reemarby, 2 accessions sonoru, 1 accession steyswer, 1 accession ruromi, 1 accession tamarby, 1 accession swaswer, 1 accession stawcharbu, 1 accession steecharbu, 1 accession stoycharbu, 1 accession swyswer, 1 accession kanoru, 1 accession kuhuru, 3 accessions, 2 variants veymarby, 1 accession swacharbu, 5 accessions swycharbu, 1 accession swucharbu, 1 accession deevar, 1 accession kenoru, 1 accession muzor, 3 accessions koyslo, 2 accessions bychawbu, 1 accession sworcharbu, 4 accessions sweycharbu, 1 accession sworswer, 2 accessions loslo, 2 accessions swoyswer, 2 accessions jawvar, 1 accession marzor, 11 accessions boswey, 1 accession chermarby, 1 accession tosoybo, 1 accession chormarby, 4 accessions beyswey, 2 accessions kovar, 1 accession boyswey, 1 accession deeswey, 5 accessions dychawbu, 1 accession deyswey, 3 accessions dochawbu, 1 accession darchawbu, 1 accession kervar, 1 accession morzor, 32 accessions 2 variants nahari, 6 accessions derchawbu, 1 accession foyswey, 1 accession roromi, 33 accessions poskoy, 2 accessions deychawbu, 1 accession dorchawbu, 1 accession geeswey, 1 accession doychawbu, 3 accessions jyswey, 1 accession swarpy, 9 accessions jeeswey, 1 accession nozor, 2 accessions swumarby, 1 accession swawpy, 1 accession swawmarby, 1 accession luvar, 1 accession joyswey, 2 accessions slarswee, 6 accessions feechawbu, 1 accession lervar, 1 accession ZFHX2.1, 9 accessions 3 variants boloyby, 2 accessions JPH4andAP1G2, 577 accessions 35 variants starcharbu, 17 accessions C14orf165, 5 accessions 2 variants C14orf167, 140 accessions 8 variants NRL, 88 accessions, 8 variants FAM158A, 124 accessions 11 variants PSME2, 442 accessions 15 variants NEDD8_, 1130 accessions 76 variants rorslo, 8 accessions nazor, 4 accessions rowobo, 10 accessions 2 variants TINF2, 466 accessions 11 variants TGM1, 109 accessions, 9 variants RABGGTA, 445 accessions 23 variants DHRS1, 308 accessions 10 variants CIDEB, 138 accessions 7 variants RIPK3andADCY4, 388 accessions 31 variants nena, 15 accessions CBLN3, 32 accessions, 3 variants SDR39U1, 405 accessions 28 variants ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         Read more...
Annotated mRNA diagrams back to top
Bibliography:               2 articles in PubMed back to top
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e, .f, .g, .h, .i-u, .j, .k, .l, .m Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes C

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function, regulation, related genes ' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To compare alternative variants, their summarized annotations, predicted proteins, introns and exons, or to access any sequence, click the 'Alternative mRNAs features' tab. To see a specific mRNA variant diagram, sequence and annotation, click the variant name in the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

If you know more about this gene, or found errors, please share your knowledge. Thank you !