Homo sapiens gene AARS2, encoding alanyl-tRNA synthetase 2, mitochondrial (putative).
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SUMMARY back to top
RefSeq annotates one representative transcript (NM included in AceView variant.a), but Homo sapiens cDNA sequences in GenBank, dbEST, Trace and SRA, filtered against clone rearrangements, coaligned on the genome and clustered in a minimal non-redundant way by the manually supervised AceView program, support at least 5 spliced variants.

AceView synopsis, each blue text links to tables and details
Expression: According to AceView, this gene is expressed at high level, 1.5 times the average gene in this release. The sequence of this gene is defined by 162 GenBank accessions from 152 cDNA clones, some from lung (seen 17 times), brain (13), prostate (9), melanotic melanoma, cell line (7), skin (7), embryonic stem cells, cell lines H1, H7, andh9 (6), small cell carcinoma (6) and 72 other tissues. We annotate structural defects or features in 14 cDNA clones.
Alternative mRNA variants and regulation: The gene contains 25 distinct gt-ag introns. Transcription produces 7 different mRNAs, 5 alternatively spliced variants and 2 unspliced forms. There are 2 probable alternative promotors and 2 validated alternative polyadenylation sites (see the diagram). The mRNAs appear to differ by truncation of the 5' end, presence or absence of 5 cassette exons, overlapping exons with different boundaries, splicing versus retention of one intron. 1158 bp of this gene are antisense to spliced gene TMEM151BandSPATS1.aAug10, raising the possibility of regulated alternate expression.
Efficacy of translation may be reduced by the presence of a shorter translated product (uORF) initiating at an AUG upstream of the main open reading frame (in variant eAug10).
Function: There are 4 articles specifically referring to this gene in PubMed. Functionally, the gene has been proposed to participate in pathway (Aminoacyl-tRNA biosynthesis) and processes (alanyl-tRNA aminoacylation, translation). Proteins are expected to have molecular functions (alanine-tRNA ligase activity, ATP binding, metal ion binding, nucleotide binding, tRNA binding) and to localize in various compartments (mitochondrion, cytoplasm, mitochondrial matrix). A putative protein interactor has been described (MEGF10).
Protein coding potential: 5 spliced mRNAs putatively encode good proteins, altogether 5 different isoforms (1 complete, 2 COOH complete, 2 partial), some containing domains tRNA synthetases class II (A), Threonyl and Alanyl tRNA synthetase second additional domain [Pfam], a coiled coil stretch [Psort2]. The remaining 2 mRNA variants (2 unspliced; 2 partial) appear not to encode good proteins. Finally proteins from this gene may be modulated by phosphorylation, as detailed at PhosphoSite.

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12.
Map on chromosome 6, links to other databases and other names
Map: This gene AARS2 maps on chromosome 6, at 6p21.1 according to Entrez Gene. In AceView, it covers 16.03 kb, from 44281063 to 44265037 (NCBI 37, August 2010), on the reverse strand.
Links to: manual annotations from KEGG_00970, PhosphoSite, the SNP view, gene overviews from Entrez Gene 57505, GeneCards, expression data from ECgene, UniGene, molecular and other annotations from UCSC, or our GOLD analysis.
The previous AceView annotation is here.
Other names: The gene is also known as AARS2, RP11-444E17.1, AARSL, MTALARS, KIAA1270, MT-ALARS, bA444E17.1 or LOC57505, choykleybu. It has been described as probable alanyl-tRNA synthetase, mitochondrial, alaRS, alanine--tRNA ligase, alanyl-tRNA synthetase like, alanyl-tRNA synthetase-like, alanine tRNA ligase 2, mitochondrial (putative).
EC number: This gene encodes protein number: 6.1.1.7.
Closest AceView homologs in other species ?
The closest mouse gene, according to BlastP, is the AceView gene Aars2 (e=0.0).
The closest C.elegans gene, according to BlastP, is the AceView/WormGene ars-2 (e=0.0), which may contain interesting functional annotation.
The closest A.thaliana gene, according to BlastP, is the AceView gene ALATS (e= 10-172), which may contain interesting functional annotation
RNA_seq discoveries back to top
Expression/conservation in primates tissues evaluated by cross-mapping to human. back to top
AARS2 Gene expression in 15 primates, 16 tissues, from the NHPRTR project in sFPKM BAB SkeletalMuscle WholeBlood CHP Kidney Liver Lung Spleen CMC CMM Cerebellum HUM Brain Colon Heart LymphNode Ovary Testis JMI BoneMarrow MLM OWL PTM RMC RMI Pituitary SQM Thymus MST SMY RTL 2.35 4.39 2.52 1.18 0.96 0.89 1.66 1.26 4.10 11.6 3.57 3.57 3.33 2.70 5.79 2.52 1.91 4.71 3.10 6.65 3.82 3.10 2.52 2.19 3.10 2.90 4.10 3.10 2.70 2.19 3.10 2.70 2.52 7.64 2.90 2.90 5.79 5.04 5.40 6.65 8.19 7.13 5.40 8.19 5.04 2.19 6.21 5.04 2.52 5.79 2.90 1.91 3.33 4.39 3.57 1.91 3.57 3.33 2.35 2.19 2.52 2.05 2.70 2.70 1.78 1.35 4.71 3.33 6.21 2.70 5.40 4.71 3.82 5.79 3.82 4.10 4.71 2.52 6.65 3.57 5.40 3.10 5.04 4.39 3.82 5.40 4.39 5.04 4.39 5.79 4.39 5.40 6.65 6.21 2.35 3.10 5.04 3.57 4.71 5.40 1.35 1.35 1.78 2.90 1.91 1.66 1.66 2.19 1.78 1.02 1.66 3.57 6.21 5.79 4.10 2.35 5.79 4.39 4.39 4.10 8.19 6.21 8.78 6.21 2.90 4.10 2.05 2.90 4.10 4.71 7.13 4.10 3.33 5.40 3.57 4.39 1.35 2.19 1.55 2.35 4.39 6.21 4.71 2.52 4.10 3.57 3.82 5.40 4.10 1.45 0.29 5.79 4.71 4.71 2.05 3.57 3.57 Expression quantiles None Weak 1 2 3 4 5 6 7 8 10 20 This gene All genes log2 distributions RNA-seq gene expression profile across 16 selected tissues from the Non-Human Primates Reference Transcriptome Resource (link to NHPRTR project).
- Primates: Apes (HUM: Human (Illumina BodyMap 2), CHP: Chimpanzee), Old World monkeys (PTM: Pig-Tailed Macaque, JMI Japanese Macaque, RMI Rhesus Macaque Indian, RMC Rhesus Macaque Chinese, CMM Cynomolgus Macaque Mauritian, CMC Cynomolgus Macaque Chinese, BAB Olive Baboon, SMY Sooty Mangabey); New World monkeys (MST common Marmoset, SQM Squirrel Monkey, OWL Owl Monkey); and Lemurs (MLM Mouse Lemur, RTL Ring-Tailed Lemur).
- The level for significantly expressed genes is color coded in 8 equal sized bins (light to dark green). Light gray is for weak not-accurately measured expression (2 to 8 reads above intergenic background); dark gray for no expression or no sequence conservation (0 read in gene). The plot to the right shows the distribution of measured expression values in all tissues for all genes (blue) and for this gene (green), in Magic index = log2(1000 sFPKM).
You may also examine the strand-specific genome coverage plots on the experimental AceView/Magic hub at UCSC, by tissue or by species. Tracks may be slow to load; please reload if some tracks come up yellow-greenish, and thanks to UCSC for the great work!.
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          Complete gene on genome diagram: back to top
Please choose between the zoomable GIF version., and the HTML5/SVG version.
This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones.
Compact gene diagram back to top
Gene AARS2 5' 3' encoded on minus strand of chromosome 6 from 44,281,063 to 44,265,037 20418 21518 33968 25335 17807 22130 26866 27102 33987 27460 25802 21800 35778 30041 25444 24357 35472 38345 35721 41318 a [NM] 21518 33968 1049 26866 27102 33987 27460 25802 21800 44 b 35472 38345 35721 41318 c 35472 38345 35721 41318 4 d f-u g-u 14 38345 35721 e 5kb 0 246 bp exon 246 bp exon 817 bp [gt-ag] intron 16 GenBank accessions 20402 RNA-seq supporting reads 2159 UHR pooled cells 1421 Brain 1347 Blood 15381 Neuroblastoma 94 Other (also 2497 Primates bodymap) 192 bp exon 536 bp [gt-ag] intron 11 GenBank accessions 21507 RNA-seq supporting reads 2535 UHR pooled cells 1696 Brain 2040 Blood 15092 Neuroblastoma 144 Other (also 2743 Primates bodymap) 146 bp exon 228 bp [gt-ag] intron 10 GenBank accessions 33958 RNA-seq supporting reads 4130 UHR pooled cells 2604 Brain 2473 Blood 24531 Neuroblastoma 220 Other (also 4227 Primates bodymap) 168 bp exon 550 bp [gt-ag] intron 9 GenBank accessions 25326 RNA-seq supporting reads 3351 UHR pooled cells 2066 Brain 1585 Blood 18189 Neuroblastoma 135 Other (also 2517 Primates bodymap) 145 bp exon 2904 bp [gt-ag] intron 11 GenBank accessions 17796 RNA-seq supporting reads 2582 UHR pooled cells 1484 Brain 701 Blood 12946 Neuroblastoma 83 Other (also 1630 Primates bodymap) 146 bp exon 217 bp [gt-ag] intron 15 GenBank accessions 22115 RNA-seq supporting reads 3324 UHR pooled cells 1889 Brain 936 Blood 15833 Neuroblastoma 133 Other (also 967 Primates bodymap) 109 bp exon 390 bp [gt-ag] intron 19 GenBank accessions 26847 RNA-seq supporting reads 3758 UHR pooled cells 2043 Brain 1526 Blood 19374 Neuroblastoma 146 Other (also 1966 Primates bodymap) 39 bp exon 102 bp [gt-ag] intron 19 GenBank accessions 27083 RNA-seq supporting reads 3473 UHR pooled cells 2021 Brain 1840 Blood 19566 Neuroblastoma 183 Other (also 1877 Primates bodymap) 112 bp exon 493 bp [gt-ag] intron 22 GenBank accessions 33965 RNA-seq supporting reads 4082 UHR pooled cells 2563 Brain 1505 Blood 25634 Neuroblastoma 181 Other (also 2613 Primates bodymap) 134 bp exon 454 bp [gt-ag] intron 19 GenBank accessions 27441 RNA-seq supporting reads 3523 UHR pooled cells 2047 Brain 1787 Blood 19906 Neuroblastoma 178 Other (also 1974 Primates bodymap) 145 bp exon 236 bp [gt-ag] intron 18 GenBank accessions 25784 RNA-seq supporting reads 3553 UHR pooled cells 2146 Brain 1225 Blood 18669 Neuroblastoma 191 Other (also 1899 Primates bodymap) 173 bp exon 111 bp [gt-ag] intron 15 GenBank accessions 21785 RNA-seq supporting reads 2831 UHR pooled cells 1607 Brain 907 Blood 16271 Neuroblastoma 169 Other (also 1664 Primates bodymap) 114 bp exon 98 bp [gt-ag] intron 15 GenBank accessions 35763 RNA-seq supporting reads 4520 UHR pooled cells 2805 Brain 1186 Blood 27014 Neuroblastoma 238 Other (also 1321 Primates bodymap) 141 bp exon 757 bp [gt-ag] intron 20 GenBank accessions 30021 RNA-seq supporting reads 3980 UHR pooled cells 2230 Brain 1208 Blood 22400 Neuroblastoma 203 Other (also 1859 Primates bodymap) 138 bp exon 110 bp [gt-ag] intron 18 GenBank accessions 25426 RNA-seq supporting reads 3196 UHR pooled cells 2031 Brain 1234 Blood 18804 Neuroblastoma 161 Other (also 1340 Primates bodymap) 110 bp exon 155 bp [gt-ag] intron 17 GenBank accessions 24340 RNA-seq supporting reads 3217 UHR pooled cells 2092 Brain 808 Blood 18070 Neuroblastoma 153 Other (also 1629 Primates bodymap) 109 bp exon 288 bp [gt-ag] intron 24 GenBank accessions 35448 RNA-seq supporting reads 4797 UHR pooled cells 2521 Brain 1400 Blood 26527 Neuroblastoma 203 Other (also 3175 Primates bodymap) 123 bp exon 220 bp [gt-ag] intron 27 GenBank accessions 38318 RNA-seq supporting reads 5184 UHR pooled cells 2838 Brain 1583 Blood 28446 Neuroblastoma 267 Other (also 2096 Primates bodymap) 111 bp exon 595 bp [gt-ag] intron 30 GenBank accessions 35691 RNA-seq supporting reads 5073 UHR pooled cells 2763 Brain 1474 Blood 26151 Neuroblastoma 230 Other (also 1679 Primates bodymap) 84 bp exon 114 bp [gt-ag] intron 37 GenBank accessions 41281 RNA-seq supporting reads 6166 UHR pooled cells 3168 Brain 1454 Blood 30236 Neuroblastoma 257 Other (also 2001 Primates bodymap) 111 bp exon 444 bp [gt-ag] intron 31 GenBank accessions 40587 RNA-seq supporting reads 5611 UHR pooled cells 2887 Brain 1247 Blood 30653 Neuroblastoma 189 Other (also 1993 Primates bodymap) 3412 bp exon 141 accessions, NM_020745.2 some from lung (seen 15 times) brain (12), prostate (9) melanotic melanoma, cell line (7) skin (7) Validated 3' end, 1 accession Validated 3' end, 1 accession 3412 bp exon 6 bp exon 536 bp [gt-ag] intron 11 GenBank accessions 21507 RNA-seq supporting reads 2535 UHR pooled cells 1696 Brain 2040 Blood 15092 Neuroblastoma 144 Other (also 2743 Primates bodymap) 146 bp exon 228 bp [gt-ag] intron 10 GenBank accessions 33958 RNA-seq supporting reads 4130 UHR pooled cells 2604 Brain 2473 Blood 24531 Neuroblastoma 220 Other (also 4227 Primates bodymap) 168 bp exon 3962 bp [gt-ag] intron 3 GenBank accessions 1046 RNA-seq supporting reads 77 UHR pooled cells 178 Brain 30 Blood 754 Neuroblastoma 7 Other (also 73 Primates bodymap) 109 bp exon 390 bp [gt-ag] intron 19 GenBank accessions 26847 RNA-seq supporting reads 3758 UHR pooled cells 2043 Brain 1526 Blood 19374 Neuroblastoma 146 Other (also 1966 Primates bodymap) 39 bp exon 102 bp [gt-ag] intron 19 GenBank accessions 27083 RNA-seq supporting reads 3473 UHR pooled cells 2021 Brain 1840 Blood 19566 Neuroblastoma 183 Other (also 1877 Primates bodymap) 112 bp exon 493 bp [gt-ag] intron 22 GenBank accessions 33965 RNA-seq supporting reads 4082 UHR pooled cells 2563 Brain 1505 Blood 25634 Neuroblastoma 181 Other (also 2613 Primates bodymap) 134 bp exon 454 bp [gt-ag] intron 19 GenBank accessions 27441 RNA-seq supporting reads 3523 UHR pooled cells 2047 Brain 1787 Blood 19906 Neuroblastoma 178 Other (also 1974 Primates bodymap) 145 bp exon 236 bp [gt-ag] intron 18 GenBank accessions 25784 RNA-seq supporting reads 3553 UHR pooled cells 2146 Brain 1225 Blood 18669 Neuroblastoma 191 Other (also 1899 Primates bodymap) 173 bp exon 111 bp [gt-ag] intron 15 GenBank accessions 21785 RNA-seq supporting reads 2831 UHR pooled cells 1607 Brain 907 Blood 16271 Neuroblastoma 169 Other (also 1664 Primates bodymap) 114 bp exon 996 bp [gt-ag] fuzzy intron 1 GenBank accession 43 RNA-seq supporting reads 3 Brain 40 Neuroblastoma 116 bp exon 4 accessions, some from large cell carcinoma (seen once) lung (once) 116 bp exon 182 bp exon 182 bp exon 288 bp [gt-ag] intron 24 GenBank accessions 35448 RNA-seq supporting reads 4797 UHR pooled cells 2521 Brain 1400 Blood 26527 Neuroblastoma 203 Other (also 3175 Primates bodymap) 123 bp exon 220 bp [gt-ag] intron 27 GenBank accessions 38318 RNA-seq supporting reads 5184 UHR pooled cells 2838 Brain 1583 Blood 28446 Neuroblastoma 267 Other (also 2096 Primates bodymap) 111 bp exon 595 bp [gt-ag] intron 30 GenBank accessions 35691 RNA-seq supporting reads 5073 UHR pooled cells 2763 Brain 1474 Blood 26151 Neuroblastoma 230 Other (also 1679 Primates bodymap) 84 bp exon 114 bp [gt-ag] intron 37 GenBank accessions 41281 RNA-seq supporting reads 6166 UHR pooled cells 3168 Brain 1454 Blood 30236 Neuroblastoma 257 Other (also 2001 Primates bodymap) 695 bp exon 4 accessions, some from brain (seen once) breast (once), epid tumor (once) mammary adenocarcinoma cell line (once), neuroblastoma (once) 695 bp exon 109 bp exon 109 bp exon 288 bp [gt-ag] intron 24 GenBank accessions 35448 RNA-seq supporting reads 4797 UHR pooled cells 2521 Brain 1400 Blood 26527 Neuroblastoma 203 Other (also 3175 Primates bodymap) 123 bp exon 220 bp [gt-ag] intron 27 GenBank accessions 38318 RNA-seq supporting reads 5184 UHR pooled cells 2838 Brain 1583 Blood 28446 Neuroblastoma 267 Other (also 2096 Primates bodymap) 111 bp exon 595 bp [gt-ag] intron 30 GenBank accessions 35691 RNA-seq supporting reads 5073 UHR pooled cells 2763 Brain 1474 Blood 26151 Neuroblastoma 230 Other (also 1679 Primates bodymap) 84 bp exon 114 bp [gt-ag] intron 37 GenBank accessions 41281 RNA-seq supporting reads 6166 UHR pooled cells 3168 Brain 1454 Blood 30236 Neuroblastoma 257 Other (also 2001 Primates bodymap) 111 bp exon 599 bp [gt-ag] intron 1 GenBank accession 3 RNA-seq supporting reads 1 UHR pooled cells 2 Neuroblastoma 387 bp exon 1 accession from ovary from teratocarcinoma cell line 387 bp exon 663 bp exon 663 bp exon 1 accession from embryonic stem cells cell lines H1, H7, andh9 663 bp exon 218 bp exon 218 bp exon 1 accession from colon 218 bp exon 196 bp exon 196 bp exon 45 bp uORF 196 bp exon 196 bp exon 772 bp [gt-ag] intron 1 GenBank accession 13 RNA-seq supporting reads 2 UHR pooled cells 11 Neuroblastoma (also 9 Primates bodymap) 123 bp exon 123 bp exon 220 bp [gt-ag] intron 27 GenBank accessions 38318 RNA-seq supporting reads 5184 UHR pooled cells 2838 Brain 1583 Blood 28446 Neuroblastoma 267 Other (also 2096 Primates bodymap) 111 bp exon 111 bp exon 595 bp [gt-ag] intron 30 GenBank accessions 35691 RNA-seq supporting reads 5073 UHR pooled cells 2763 Brain 1474 Blood 26151 Neuroblastoma 230 Other (also 1679 Primates bodymap) 17 bp exon 17 bp exon 1 accession from testis capped 5' end, 1 accession 17 bp exon Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
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Sequences: click on the numbers to get the DNA back to top
mRNA variant mRNA matching the genome Best predicted protein 5' UTR 3' UTR uORF Upstream sequence Transcription
unit
pre-mRNA
Downstream sequence
aAug10 6208 bp 985 aa 3247 bp 2kb probably including promoter 16027 bp 1kb
bAug10 1262 bp 420 aa 2kb 8770 bp 1kb
cAug10 1195 bp 223 aa 521 bp 2kb 2412 bp 1kb
dAug10 925 bp 192 aa 345 bp 2kb 2741 bp 1kb
eAug10 447 bp 103 aa 136 bp 42 bp 2kb including Promoter 2034 bp 1kb
fAug10-unspliced 663 bp 83 aa 413 bp 2kb 663 bp 1kb
gAug10-unspliced 218 bp 65 aa 18 bp 2kb 218 bp 1kb

Gene neighbors and Navigator on chromosome 6p21.1 back to top
G D R P C C6orf223 R R TMEM63B C R CAPN11 D C R P R SLC29A1 D C I R P HSP90AB1 D C I R P TMEM151BandSPATS1 C R P CDC5L D C I R P R RPL29P16 R R G C R P MRPL14 C R R C R P SLC35B2 D C I R P NFKBIE C R P TCTE1 C I R P AARS2 R R R 100kb 0 LOC100132354, 4 accessions 2 variants plyfloybu, 1 accession C6orf223, 53 accessions 4 variants gawjee, 1 accession TMEM63B, 229 accessions 17 variants CAPN11, 84 accessions 8 variants shawbloy, 13 accessions 2 variants SLC29A1, 698 accessions 36 variants HSP90AB1, 415 accessions 25 variants TMEM151BandSPATS1, 147 accessions 12 variants CDC5L, 484 accessions 7 variants miyora, 4 accessions, 2 variants farglawby, 7 accessions 2 variants cherbloy, 1 accession snorglarby, 2 accessions klarsloyby, 7 accessions lersperby, 2 accessions wykleybu, 4 accessions wukleybu, 1 accession sperglarby, 1 accession speyglarby, 2 accessions sporglarby, 1 accession zorkleybu, 1 accession stoglarby, 1 accession stawglarby, 1 accession vyspybu, 1 accession vospybu, 1 accession niyume, 1 accession swawglarby, 1 accession spersoyby, 1 accession cheekleybu, 1 accession cherkleybu, 2 accessions swoysoyby, 2 accessions sworglarby, 1 accession swoyglarby, 1 accession cheykleybu, 1 accession byglawby, 1 accession boglawby, 5 accessions geyjee, 2 accessions veespybu, 1 accession berglawby, 1 accession sakeya, 1 accession vysperby, 1 accession vorsperby, 1 accession shukleybu, 1 accession sikeya, 1 accession daglawby, 1 accession sukeya, 1 accession dyglawby, 3 accessions voyspybu, 1 accession doglawby, 1 accession wyspybu, 1 accession klarvabo, 1 accession dawglawby, 5 accessions bleykleybu, 1 accession wospybu, 1 accession deeglawby, 3 accessions sekeya, 1 accession deyglawby, 1 accession dorglawby, 1 accession jyjee, 1 accession doyglawby, 1 accession dawtaby, 1 accession husiya, 1 accession snoyglarby, 1 accession spyglarby, 1 accession tarspybu, 1 accession gojee, 1 accession tawspybu, 1 accession chorbloy, 3 accessions teespybu, 1 accession terspybu, 1 accession teyspybu, 2 accessions spoglarby, 1 accession sparglarby, 3 accessions RPL29P16, 1 accession shybloy, 3 accessions spoyglarby, 3 accessions styglarby, 1 accession stuglarby, 1 accession starglarby, 1 accession vaspybu, 2 accessions sterglarby, 1 accession storglarby, 1 accession stoyglarby, 2 accessions varspybu, 1 accession chykleybu, 1 accession swyglarby, 1 accession swoglarby, 1 accession swarglarby, 2 accessions mawsperby, 1 accession vawspybu, 1 accession shubloy, 1 accession shobloy, 3 accessions tokeya, 1 accession beytaby, 10 accessions beeglawby, 1 accession beyglawby, 1 accession veyspybu, 1 accession borglawby, 1 accession vorspybu, 1 accession duglawby, 1 accession waspybu, 1 accession nuyume, 1 accession darglawby, 2 accessions sheekleybu, 1 accession bortaby, 2 accessions databy, 1 accession flarkleybu, 2 accessions jojee, 3 accessions, 2 variants flerkleybu, 1 accession klawvabo, 1 accession faglawby, 1 accession fyglawby, 1 accession shorbloy, 1 accession foglawby, 1 accession chersperby, 2 accessions zaspybu, 1 accession bawwawbo, 4 accessions 2 variants renora, 16 accessions 5 variants LOC652990, 34 accessions 2 variants MRPL14, 275 accessions 8 variants sharbloy, 10 accessions 3 variants fleybloyby, 14 accessions 2 variants SLC35B2, 428 accessions 11 variants NFKBIE, 195 accessions 5 variants TCTE1, 43 accessions, 4 variants AARS2, 158 accessions 7 variants plufloybu, 3 accessions 2 variants jujee, 6 accessions fuglawby, 2 accessions 2 variants ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         Read more...
Annotated mRNA diagrams back to top
Bibliography:               4 articles in PubMed back to top
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e, .f-u, .g-u Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes CI

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function, regulation, related genes ' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To compare alternative variants, their summarized annotations, predicted proteins, introns and exons, or to access any sequence, click the 'Alternative mRNAs features' tab. To see a specific mRNA variant diagram, sequence and annotation, click the variant name in the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

If you know more about this gene, or found errors, please share your knowledge. Thank you !