Display Settings:

Format

Send to:

Choose Destination
HomoloGene:23664. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SEMA3D,  H.sapiens
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
NP_689967.2
777 aa
SEMA3D,  P.troglodytes
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
XP_527805.2
777 aa
SEMA3D,  M.mulatta
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
XP_001107897.1
777 aa
SEMA3D,  C.lupus
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
XP_533138.2
777 aa
SEMA3D,  B.taurus
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
NP_001193025.1
776 aa
Sema3d,  M.musculus
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
NP_083158.3
777 aa
Sema3d,  R.norvegicus
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
NP_001098103.1
777 aa
SEMA3D,  G.gallus
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
NP_990704.1
761 aa
sema3d,  X.tropicalis
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
XP_002935293.2
776 aa
sema3d,  D.rerio
semaphorin 3d
NP_571123.1
764 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Identification and tissue-specific expression of a novel isoform of Semaphorin 3D.
Takahashi K, et al. Biochim Biophys Acta 1790, 395-400 (2009).
Semaphorin 3d guides laterality of retinal ganglion cell projections in zebrafish.
Sakai JA & Halloran MC. Development 133, 1035-44 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Sema (cl15693)
  The Sema domain, a protein interacting module, of semaphorins and plexins.
DUF560 (pfam04575)
  Protein of unknown function (DUF560).
PSI (cl02601)
  A cysteine rich repeat found in several different extracellular receptors. The function of the repeat is unknown. Three copies of the repeat are found Plexin. Two copies of the repeat are found in mahogany protein. A related C. elegans protein contains four copies of the repeat. The Met receptor contains a single copy of the repeat. The Pfam alignment shows 6 conserved cysteine residues that may form three conserved disulphide bridges, whereas shows 8 conserved cysteines. The pattern of conservation suggests that cysteines 5 and 7 (that are not absolutely conserved) form a disulphide bridge (Personal observation. A Bateman).
Ig (cl11960)
  Immunoglobulin domain.
Sema (cl15693)
  The Sema domain, a protein interacting module, of semaphorins and plexins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sema3d includes H.sapiens SEMA3D and R.norvegicus Sema3d.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

 

 

 

Support Center