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HomoloGene:3680. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PCYT1A,  H.sapiens
phosphate cytidylyltransferase 1, choline, alpha
NP_005008.2
367 aa
PCYT1A,  P.troglodytes
phosphate cytidylyltransferase 1, choline, alpha
XP_526433.2
205 aa
PCYT1A,  C.lupus
phosphate cytidylyltransferase 1, choline, alpha
XP_535776.1
367 aa
PCYT1A,  B.taurus
phosphate cytidylyltransferase 1, choline, alpha
NP_001098522.1
406 aa
Pcyt1a,  M.musculus
phosphate cytidylyltransferase 1, choline, alpha isoform
NP_001156631.1
367 aa
Pcyt1a,  R.norvegicus
phosphate cytidylyltransferase 1, choline, alpha
NP_511177.2
367 aa
PCYT1A,  G.gallus
phosphate cytidylyltransferase 1, choline, alpha
XP_422725.3
485 aa
pcyt1a,  X.tropicalis
phosphate cytidylyltransferase 1, choline, alpha
XP_002934091.2
400 aa
pcyt1aa,  D.rerio
phosphate cytidylyltransferase 1, choline, alpha a
NP_001017634.1
374 aa
Cct2,  D.melanogaster
CTP:phosphocholine cytidylyltransferase 2
NP_647622.1
381 aa
Cct1,  D.melanogaster
CTP:phosphocholine cytidylyltransferase 1
NP_728628.1
526 aa
AgaP_AGAP002263,  A.gambiae
AgaP_AGAP002263
XP_003436073.1
416 aa
pcyt-1,  C.elegans
pcyt-1
NP_001033539.1
362 aa
Y18H1A.11,  C.elegans
Y18H1A.11
NP_871893.1
272 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Phosphatidylcholine protects against steatosis in mice but not non-alcoholic steatohepatitis.
Niebergall LJ, et al. Biochim Biophys Acta 1811, 1177-85 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PLN02413 (PLN02413)
  choline-phosphate cytidylyltransferase.
nt_trans (cl00015)
  nucleotidyl transferase superfamily.
nt_trans (cl00015)
  nucleotidyl transferase superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pcyt1a includes H.sapiens PCYT1A and R.norvegicus Pcyt1a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (13 transcripts, 9 species)
Mammalia - mammals (10 transcripts, 8 species)
Amphibia - amphibians (4 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 10 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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