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HomoloGene:110436. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MBL2,  H.sapiens
mannose-binding lectin (protein C) 2, soluble
NP_000233.1
248 aa
MBL2,  P.troglodytes
mannose-binding lectin (protein C) 2, soluble
NP_001009005.1
248 aa
MBL2,  M.mulatta
mannose-binding lectin (protein C) 2, soluble
NP_001099005.1
248 aa
MBL2,  B.taurus
mannose-binding lectin (protein C) 2, soluble
NP_776532.1
249 aa
Mbl2,  M.musculus
mannose-binding lectin (protein C) 2
NP_034906.1
244 aa
Mbl2,  R.norvegicus
mannose-binding lectin (protein C) 2
NP_073195.2
244 aa
LOC100911854,  R.norvegicus
mannose-binding protein C-like
XP_003749136.1
244 aa
MBL2,  G.gallus
mannose-binding lectin (protein C) 2, soluble
NP_989680.2
254 aa
LOC100496214,  X.tropicalis
pulmonary surfactant-associated protein D-like
XP_002933943.1
268 aa
hbl3,  D.rerio
hexose-binding lectin 3
NP_571645.2
251 aa
hbl4,  D.rerio
hexose-binding lectin 4
NP_001108197.1
245 aa
hbl1,  D.rerio
hexose-binding lectin 1
XP_001341915.1
254 aa
hbl2,  D.rerio
hexose-binding lectin 2
XP_695347.1
253 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Chronic infections, due to MBL deficiency.
Diabetes mellitus, gestational, susceptibility to.
Mannose-binding protein deficiency.
Meningococcal disease, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

MBL2 variations and malaria susceptibility in Indian populations.
Jha AN, et al. Infect Immun 82, 52-61 (2014).
Mannose-binding lectin 2 gene and risk of adult glioma.
Michaud DS, et al. PLoS One 8, e61117 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Surfac_D-trimer (pfam09006)
  Lung surfactant protein D coiled-coil trimerisation.
CLECT (cl02432)
  C-type lectin (CTL)/C-type lectin-like (CTLD) domain.
CLECT (cl02432)
  C-type lectin (CTL)/C-type lectin-like (CTLD) domain.
Collagen (cl19732)
  Collagen triple helix repeat (20 copies).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mbl2 includes H.sapiens MBL2 and R.norvegicus Mbl2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (3 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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