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HomoloGene:129876. Gene conserved in Catarrhini Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

KLLN,  H.sapiens
killin, p53-regulated DNA replication inhibitor
NP_001119521.1
178 aa
KLLN,  P.troglodytes
killin, p53-regulated DNA replication inhibitor
XP_003312729.1
178 aa
LOC100426503,  M.mulatta
killin-like
XP_002805787.1
179 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.

Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest.
Nizialek EA, et al. Hum Mol Genet 22, 2451-61 (2013).
Analysis of KLLN as a high-penetrance breast cancer predisposition gene.
Thompson ER, et al. Breast Cancer Res Treat 134, 543-7 (2012).
Killin is a p53-regulated nuclear inhibitor of DNA synthesis.
Cho YJ & Liang P. Proc Natl Acad Sci U S A 105, 5396-401 (2008).




UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (1 transcript, 1 species)

 

 

 

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