HomoloGene

Orthologs Genome Browser BLAST

RefSeq Sequences

Showing 5 of 40 (by status, accession number)

Transcript	nt	Protein	aa	Isoform	Status
NM_001142327.1	3,801	NP_001135799.1	760	a	RefSeq Select
NM_021145.3	4,052	NP_066968.3	760	a	curated
NM_001142326.1	3,684	NP_001135798.1	672	b	curated
NR_024549.1	4,012				curated
NR_024550.1	3,973				curated

Search the Nucleotide and Protein databases for more Homo sapiens DMTF1 sequences

HomoloGene:8017. Gene conserved in Euteleostomi

Genes Genes identified as putative homologs of one another during the construction of HomoloGene.		Proteins Proteins used in sequence comparisons and their conserved domain architectures.
	DMTF1, H.sapiens cyclin D binding myb-like transcription factor 1		NP_001135799.1 760 aa
	DMTF1, P.troglodytes cyclin D binding myb-like transcription factor 1		XP_001162461.2 759 aa
	DMTF1, M.mulatta cyclin D binding myb-like transcription factor 1		XP_001107093.1 761 aa
	DMTF1, C.lupus cyclin D binding myb-like transcription factor 1		XP_005628510.1 762 aa
	DMTF1, B.taurus cyclin D binding myb-like transcription factor 1		XP_005205364.1 761 aa
	Dmtf1, M.musculus cyclin D binding myb-like transcription factor 1		NP_035936.3 761 aa
	DMTF1, G.gallus cyclin D binding myb-like transcription factor 1		NP_001074332.2 767 aa
	dmtf1, X.tropicalis cyclin D binding myb-like transcription factor 1		XP_002935299.2 748 aa
	dmtf1, D.rerio cyclin D binding myb-like transcription factor 1		NP_001002665.1 645 aa

Protein Alignments

Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Pairwise alignments generated using BLAST

Regenerate Alignments

Publications Articles associated with genes and sequences of this homology group.
Regulation of murine hematopoietic stem cell quiescence by Dmtf1. Kobayashi M & Srour EF. Blood 118, 6562-71 (2011).
Role of DMP1 and its future in lung cancer diagnostics. Sugiyama T, et al. Expert Rev Mol Diagn 8, 435-47 (2008).
Emerging roles of DMP1 in lung cancer. Inoue K, et al. Cancer Res 68, 4487-90 (2008).
Dmp1 and tumor suppression. Inoue K, et al. Oncogene 26, 4329-35 (2007).
Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns. Tschan MP, et al. J Biol Chem 278, 42750-60 (2003).
Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis. Inoue K, et al. Genes Dev 14, 1797-809 (2000).
Regulation of the CD13/aminopeptidase N gene by DMP1, a transcription factor antagonized by D-type cyclins. Inoue K, et al. J Biol Chem 273, 29188-94 (1998).
Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts. Boraska V, et al. PLoS One 7, e31369 (2012).
The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias. Tschan MP, et al. Leukemia 22, 1087-90 (2008).
Repression of Dmp1 and Arf transcription by anthracyclins: critical roles of the NF-kappaB subunit p65. Taneja P, et al. Oncogene 26, 7457-66 (2007).
See all (23)

Conserved Domains Conserved Domains from CDD found in protein sequences by rpsblast searching.
Myb_DNA-bind_6 (pfam13921) Myb-like DNA-binding domain.
SANT (cl17250) 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The ...

Related Homology Resources Links to curated and computed homology information found in other databases.
MGI:1344415 Orthology group for M.musculus Dmtf1 includes H.sapiens DMTF1 and R.norvegicus Dmtf1.

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