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HomoloGene:11131. Gene conserved in Bilateria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

CHP2,  H.sapiens
calcineurin-like EF-hand protein 2
196 aa
CHP2,  P.troglodytes
calcineurin-like EF hand protein 2
196 aa
CHP2,  M.mulatta
calcineurin-like EF hand protein 2
196 aa
CHP2,  B.taurus
calcineurin B homologous protein 2
196 aa
Chp2,  M.musculus
calcineurin-like EF hand protein 2
196 aa
Chp2,  R.norvegicus
calcineurin-like EF hand protein 2
196 aa
chp2,  D.rerio
calcineurin-like EF hand protein 2
195 aa
pbo-1,  C.elegans
196 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Calcineurin homologous protein: a multifunctional Ca2+-binding protein family.
Di Sole F, et al. Am J Physiol Renal Physiol 303, F165-79 (2012).
[Expression of a tumor related gene chp2 in leukemia cells].
Li B, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16, 734-7 (2008).
A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange.
Lin X & Barber DL. Proc Natl Acad Sci U S A 93, 12631-6 (1996).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EFh (cd00051)
  EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Chp2 includes H.sapiens CHP2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (7 transcripts, 7 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amniota - vertebrates (1 transcript, 1 species)

Chromadorea - nematodes (1 transcript, 1 species)




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