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HomoloGene:14135. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ARHGAP18,  H.sapiens
Rho GTPase activating protein 18
NP_277050.2
663 aa
ARHGAP18,  P.troglodytes
Rho GTPase activating protein 18
XP_001168191.2
663 aa
ARHGAP18,  M.mulatta
Rho GTPase activating protein 18
XP_001105288.1
663 aa
ARHGAP18,  C.lupus
Rho GTPase activating protein 18
XP_533497.3
662 aa
ARHGAP18,  B.taurus
Rho GTPase activating protein 18
NP_001104242.1
536 aa
Arhgap18,  M.musculus
Rho GTPase activating protein 18
NP_789807.1
663 aa
Arhgap18,  R.norvegicus
Rho GTPase activating protein 18
NP_001164046.1
665 aa
ARHGAP18,  G.gallus
Rho GTPase activating protein 18
XP_419743.3
652 aa
arhgap18,  X.tropicalis
Rho GTPase activating protein 18
NP_001072336.1
662 aa
LOC101734415,  X.tropicalis
rho GTPase-activating protein 18-like
XP_004920294.1
531 aa
LOC100004252,  D.rerio
rho GTPase-activating protein 18-like
XP_001343601.5
517 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Screening for replication of genome-wide SNP associations in sporadic ALS.
Cronin S, et al. Eur J Hum Genet 17, 213-8 (2009).
Genetically distinct subsets within ANCA-associated vasculitis.
Lyons PA, et al. N Engl J Med 367, 214-23 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RhoGAP (cl02570)
  RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Arhgap18 includes H.sapiens ARHGAP18 and R.norvegicus Arhgap18.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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