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HomoloGene:6262. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ADAT2,  H.sapiens
adenosine deaminase, tRNA-specific 2
NP_872309.2
191 aa
ADAT2,  P.troglodytes
adenosine deaminase, tRNA-specific 2
XP_518775.2
191 aa
ADAT2,  M.mulatta
adenosine deaminase, tRNA-specific 2
XP_001091638.1
191 aa
ADAT2,  C.lupus
adenosine deaminase, tRNA-specific 2
XP_003432552.1
192 aa
ADAT2,  B.taurus
adenosine deaminase, tRNA-specific 2
NP_001029952.1
191 aa
Adat2,  M.musculus
adenosine deaminase, tRNA-specific 2
NP_080024.3
191 aa
Adat2,  R.norvegicus
adenosine deaminase, tRNA-specific 2
NP_001108500.1
191 aa
ADAT2,  G.gallus
adenosine deaminase, tRNA-specific 2
XP_419709.1
172 aa
adat2,  X.tropicalis
adenosine deaminase, tRNA-specific 2
NP_001072562.1
170 aa
adat2,  D.rerio
adenosine deaminase, tRNA-specific 2, TAD2 homolog (S. cerevisiae)
NP_001076566.1
206 aa
CG5292,  D.melanogaster
CG5292
NP_650610.1
160 aa
AgaP_AGAP013244,  A.gambiae
AgaP_AGAP013244
XP_003436275.1
167 aa
CELE_JC8.4,  C.elegans
CELE_JC8.4
NP_502546.1
176 aa
tad2,  S.pombe
tad2
NP_596505.2
389 aa
emb2191,  A.thaliana
emb2191
NP_564523.3
182 aa
Os03g0321900,  O.sativa
Os03g0321900
NP_001049964.1
183 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

RNA editing by adenosine deaminases generates RNA and protein diversity.
Schaub M & Keller W. Biochimie 84, 791-803 (2002).
Regulating gene expression in the Drosophila germ line.
Rangan P, et al. Cold Spring Harb Symp Quant Biol 73, 1-8 (2008).
Temporal and spatial control of germ-plasm RNAs.
Rangan P, et al. Curr Biol 19, 72-7 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
cytidine_deaminase-like (cl00269)
  Cytidine and deoxycytidylate deaminase zinc-binding region. The family contains cytidine deaminases, nucleoside deaminases, deoxycytidylate deaminases and riboflavin deaminases. Also included are the apoBec family of mRNA editing enzymes. All members ...
NK (cl17190)
  Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Adat2 includes H.sapiens ADAT2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 8 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Ascidiacea - tunicates (3 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 8 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (15 transcripts, 14 species)
Liliopsida - monocots (2 transcripts, 2 species)
Coniferopsida - conifers (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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