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HomoloGene:77719. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RGS11,  H.sapiens
regulator of G-protein signaling 11
NP_899180.1
467 aa
RGS11,  P.troglodytes
regulator of G-protein signaling 11
XP_003314940.2
597 aa
RGS11,  M.mulatta
regulator of G-protein signaling 11
XP_001083719.1
446 aa
RGS11,  C.lupus
regulator of G-protein signaling 11
XP_854319.3
465 aa
RGS11,  B.taurus
regulator of G-protein signaling 11
NP_001069282.2
465 aa
Rgs11,  M.musculus
regulator of G-protein signaling 11
NP_001074538.1
466 aa
Rgs11,  R.norvegicus
regulator of G-protein signaling 11
NP_062211.1
467 aa
RGS11,  G.gallus
regulator of G-protein signaling 11
XP_001231808.2
473 aa
rgs9,  X.tropicalis
regulator of G-protein signaling 9
NP_001096497.1
469 aa
rgs11,  D.rerio
regulator of G-protein signaling 11
NP_001104631.1
359 aa
AgaP_AGAP000232,  A.gambiae
AgaP_AGAP000232
XP_310900.5
1282 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

RGS7 and -11 complexes accelerate the ON-bipolar cell light response.
Zhang J, et al. Invest Ophthalmol Vis Sci 51, 1121-9 (2010).
Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites.
Chen FS, et al. Invest Ophthalmol Vis Sci 51, 686-93 (2010).
RGS11 interacts preferentially with R7BP over Galpha(oa)--characterization of Gbeta5-free RGS11.
Saleem Y & Kim KS. Biochem Biophys Res Commun 386, 65-70 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
GGL (cl00069)
  G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors.
DEP (cl02442)
  DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
RGS (cl02565)
  Regulator of G protein signaling (RGS) domain superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rgs11 includes H.sapiens RGS11 and R.norvegicus Rgs11.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (3 transcripts, 1 species)
Amphibia - amphibians (3 transcripts, 2 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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