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HomoloGene:7442. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MAP4K4,  H.sapiens
mitogen-activated protein kinase kinase kinase kinase 4
NP_663719.2
1273 aa
MAP4K4,  P.troglodytes
mitogen-activated protein kinase kinase kinase kinase 4
XP_515665.3
1280 aa
MAP4K4,  M.mulatta
mitogen-activated protein kinase kinase kinase kinase 4
XP_001107420.2
1266 aa
MAP4K4,  C.lupus
mitogen-activated protein kinase kinase kinase kinase 4
XP_005626291.1
1335 aa
MAP4K4,  B.taurus
mitogen-activated protein kinase kinase kinase kinase 4
XP_003586662.2
1239 aa
Map4k4,  M.musculus
mitogen-activated protein kinase kinase kinase kinase 4
NP_001239129.1
1288 aa
Map4k4,  R.norvegicus
mitogen-activated protein kinase kinase kinase kinase 4
NP_001100374.1
1178 aa
MAP4K4,  G.gallus
mitogen-activated protein kinase kinase kinase kinase 4
XP_416913.4
1330 aa
map4k4,  X.tropicalis
mitogen-activated protein kinase kinase kinase kinase 4
XP_002934552.1
1403 aa
wu:fa03e11,  D.rerio
wu:fa03e11
XP_001343426.5
1006 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

TNF-α involvement in insulin resistance induced by experimental scorpion envenomation.
Ait-Lounis A & Laraba-Djebari F. PLoS Negl Trop Dis 6, e1740 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
DARPP-32 (pfam05395)
  Protein phosphatase inhibitor 1/DARPP-32.
CNH (cl02434)
  CNH domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Map4k4 includes H.sapiens MAP4K4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (38 transcripts, 10 species)
Mammalia - mammals (18 transcripts, 9 species)
Aves - birds (3 transcripts, 1 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (2 transcripts, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 9 species)
Arachnida - arachnids (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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