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HomoloGene:531. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GSR,  H.sapiens
glutathione reductase
NP_000628.2
522 aa
GSR,  P.troglodytes
glutathione reductase
XP_519696.2
522 aa
GSR,  C.lupus
glutathione reductase
XP_532813.2
521 aa
GSR,  B.taurus
glutathione reductase
NP_001107662.1
519 aa
Gsr,  M.musculus
glutathione reductase
NP_034474.4
500 aa
Gsr,  R.norvegicus
glutathione reductase
NP_446358.2
410 aa
GSR,  G.gallus
glutathione reductase
XP_001235017.2
517 aa
gsr,  X.tropicalis
glutathione reductase
NP_001120626.2
590 aa
gsr,  D.rerio
glutathione reductase
NP_001018390.1
425 aa
gsr-1,  C.elegans
gsr-1
NP_001021220.1
473 aa
GLR1,  S.cerevisiae
GLR1
NP_015234.1
483 aa
KLLA0E24069g,  K.lactis
KLLA0E24069g
XP_455036.1
484 aa
AGOS_AGR196W,  E.gossypii
AGOS_AGR196W
NP_986862.1
480 aa
pgr1,  S.pombe
pgr1
NP_595589.1
464 aa
MGG_12749,  M.oryzae
MGG_12749
XP_003716743.1
508 aa
NCU03339,  N.crassa
NCU03339
XP_956448.1
468 aa
GR,  A.thaliana
GR
NP_191026.1
565 aa
Os03g0163300,  O.sativa
Os03g0163300
NP_001049057.1
555 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hemolytic anemia due to glutathione reductase deficiency.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Pyr_redox (pfam00070)
  Pyridine nucleotide-disulphide oxidoreductase.
Pyr_redox_dim (pfam02852)
  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
Pyr_redox (pfam00070)
  Pyridine nucleotide-disulphide oxidoreductase.
Pyr_redox_dim (pfam02852)
  Pyridine nucleotide-disulphide oxidoreductase, dimerization domain.
NAD_binding_8 (cl19134)
  NAD(P)-binding Rossmann-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gsr includes H.sapiens GSR and R.norvegicus Gsr.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (12 transcripts, 8 species)
Mammalia - mammals (10 transcripts, 9 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Turbellaria - flatworms (2 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (15 transcripts, 3 species)
Pezizomycetes - ascomycetes (2 transcripts, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Oomycetes
Pythiales - oomycetes (2 transcripts, 1 species)
Peronosporales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (2 transcripts, 1 species)

 

 

 

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