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HomoloGene:40690. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

AEBP2,  H.sapiens
AE binding protein 2
517 aa
AEBP2,  P.troglodytes
AE binding protein 2
496 aa
LOC704080,  M.mulatta
zinc finger protein AEBP2-like
478 aa
AEBP2,  C.lupus
AE binding protein 2
316 aa
AEBP2,  B.taurus
AE binding protein 2
511 aa
Aebp2,  M.musculus
AE binding protein 2
496 aa
Aebp2,  R.norvegicus
AE binding protein 2
308 aa
AEBP2,  G.gallus
AE binding protein 2
372 aa
aebp2,  D.rerio
AE binding protein 2
415 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.
Kim H, et al. Nucleic Acids Res 37, 2940-50 (2009).
Substrate preferences of the EZH2 histone methyltransferase complex.
Martin C, et al. J Biol Chem 281, 8365-70 (2006).
Aebp2 as an epigenetic regulator for neural crest cells.
Kim H, et al. PLoS One 6, e25174 (2011).
Jarid2 and PRC2, partners in regulating gene expression.
Li G, et al. Genes Dev 24, 368-80 (2010).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
COG5048 (COG5048)
  FOG: Zn-finger [General function prediction only].
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Aebp2 includes H.sapiens AEBP2 and R.norvegicus Aebp2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Insecta - insects (1 transcript, 1 species)




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