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HomoloGene:3890. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HAGH,  H.sapiens
hydroxyacylglutathione hydrolase
NP_005317.2
308 aa
HAGH,  P.troglodytes
hydroxyacylglutathione hydrolase
XP_510739.4
260 aa
HAGH,  M.mulatta
hydroxyacylglutathione hydrolase
XP_001090907.1
308 aa
HAGH,  C.lupus
hydroxyacylglutathione hydrolase
XP_537013.2
309 aa
HAGH,  B.taurus
hydroxyacylglutathione hydrolase
NP_001030351.1
308 aa
Hagh,  M.musculus
hydroxyacyl glutathione hydrolase
NP_077246.2
309 aa
Hagh,  R.norvegicus
hydroxyacyl glutathione hydrolase
NP_203500.2
309 aa
HAGH,  G.gallus
hydroxyacylglutathione hydrolase
NP_001012807.1
310 aa
hagh,  X.tropicalis
hydroxyacylglutathione hydrolase
NP_001135503.1
313 aa
hagh,  D.rerio
hydroxyacylglutathione hydrolase
NP_956337.1
260 aa
CG4365,  D.melanogaster
CG4365
NP_649258.1
305 aa
AgaP_AGAP000416,  A.gambiae
AgaP_AGAP000416
XP_003436986.1
303 aa
Y17G7B.3,  C.elegans
Y17G7B.3
NP_496556.1
260 aa
GLY2,  A.thaliana
GLY2
NP_187696.1
258 aa
Os03g0332400,  O.sativa
Os03g0332400
NP_001050016.1
258 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Glyoxalase II deficiency.



Publications
Articles associated with genes and sequences of this homology group.

The metal ion requirements of Arabidopsis thaliana Glx2-2 for catalytic activity.
Limphong P, et al. J Biol Inorg Chem 15, 249-58 (2010).
Expression of glyoxalase I and II in normal and breast cancer tissues.
Rulli A, et al. Breast Cancer Res Treat 66, 67-72 (2001).
cDNA cloning and characterization of a rat spermatogenesis-associated protein RSP29.
Ji X, et al. Biochem Biophys Res Commun 241, 714-9 (1997).
Molecular cloning and characterization of the thiolesterase glyoxalase II from Arabidopsis thaliana.
Ridderström M & Mannervik B. Biochem J 322 ( Pt 2), 449-54 (1997).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Lactamase_B (cl00446)
  Metallo-beta-lactamase superfamily.
Lactamase_B (cl00446)
  Metallo-beta-lactamase superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hagh includes H.sapiens HAGH and R.norvegicus Hagh.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 13 species)
Actinopterygii - bony fishes (13 transcripts, 11 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (12 transcripts, 11 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (33 transcripts, 31 species)
Liliopsida - monocots (9 transcripts, 9 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Bryopsida - mosses (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Oomycetes
Pythiales - oomycetes (1 transcript, 1 species)

 

 

 

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