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HomoloGene:1679. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

JUN,  H.sapiens
jun proto-oncogene
NP_002219.1
331 aa
JUN,  P.troglodytes
jun proto-oncogene
XP_513442.2
331 aa
JUN,  M.mulatta
jun proto-oncogene
XP_001114665.1
334 aa
JUN,  C.lupus
jun proto-oncogene
XP_005620302.1
341 aa
JUN,  B.taurus
jun proto-oncogene
NP_001071295.1
303 aa
Jun,  M.musculus
jun proto-oncogene
NP_034721.1
334 aa
Jun,  R.norvegicus
jun proto-oncogene
NP_068607.1
334 aa
JUN,  G.gallus
jun proto-oncogene
NP_001026460.1
310 aa
jun,  X.tropicalis
jun proto-oncogene
XP_002931634.1
312 aa
jun,  D.rerio
jun proto-oncogene
NP_956281.1
308 aa
AgaP_AGAP006386,  A.gambiae
AgaP_AGAP006386
XP_001688864.1
347 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Phosphorylation of ATF2 and interaction with NFY induces c-Jun in the gonadotrope.
Lindaman LL, et al. Mol Cell Endocrinol 365, 316-26 (2013).
Human serum protein enhances HIV-1 replication and up-regulates the transcription factor AP-1.
Perdomo MF, et al. Proc Natl Acad Sci U S A 109, 17639-44 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
bZIP_1 (pfam00170)
  bZIP transcription factor.
Jun (pfam03957)
  Jun-like transcription factor.
Jun (pfam03957)
  Jun-like transcription factor.
B_zip1 (cl02576)
  basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Jun includes H.sapiens JUN and R.norvegicus Jun.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (16 transcripts, 9 species)
Mammalia - mammals (13 transcripts, 9 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 10 species)
Arachnida - arachnids (2 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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