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HomoloGene:1504. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ETV4,  H.sapiens
ets variant 4
NP_001073143.1
484 aa
ETV4,  P.troglodytes
ets variant 4
XP_511536.3
484 aa
ETV4,  M.mulatta
ets variant 4
XP_002800568.1
484 aa
ETV4,  C.lupus
ets variant 4
XP_857325.4
485 aa
ETV4,  B.taurus
ets variant 4
XP_005221005.1
485 aa
Etv4,  M.musculus
ets variant gene 4 (E1A enhancer binding protein, E1AF)
NP_032841.2
485 aa
Etv4,  R.norvegicus
ets variant 4
NP_001101769.1
486 aa
etv4,  D.rerio
ets variant gene 4
NP_571500.1
491 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Impaired c-src activation and motility defects in PEA3-null fibroblasts.
Chaar ZY, et al. Biochim Biophys Acta 1823, 2237-42 (2012).
A positive role for PEA3 in HER2-mediated breast tumour progression.
Myers E, et al. Br J Cancer 95, 1404-9 (2006).
Genomic structure and promoter activity of the E1AF gene, a member of the ETS oncogene family.
Ishida S, et al. Biochem Biophys Res Commun 339, 325-30 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ets (pfam00178)
  Ets-domain.
ETS_PEA3_N (pfam04621)
  PEA3 subfamily ETS-domain transcription factor N terminal domain.
ETS_PEA3_N (pfam04621)
  PEA3 subfamily ETS-domain transcription factor N terminal domain.
Ets (cl02599)
  Ets-domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Etv4 includes H.sapiens ETV4 and R.norvegicus Etv4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (10 transcripts, 9 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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